Zi Yang, Ji Luo, Wenbo Zhang, Jieni Lei, Chaoshui Liu, Yaqian Li
{"title":"铑（III）催化的 2-芳基-3H-吲哚的直接 C-H 活化：4-庚芳基吡唑的合成策略。","authors":"Zi Yang, Ji Luo, Wenbo Zhang, Jieni Lei, Chaoshui Liu, Yaqian Li","doi":"10.1039/d4ob01655f","DOIUrl":null,"url":null,"abstract":"<p><p>A novel protocol for synthesizing 4-heteroaryl pyrazoles from readily available 2-aryl-3<i>H</i>-indoles and diazopyrazolones through the rhodium(III)-catalyzed C-H bond activation has been achieved. This redox-neutral strategy features powerful reactivity, tolerates various functional groups, and proceeds with moderate yields under mild reaction conditions.</p>","PeriodicalId":96,"journal":{"name":"Organic & Biomolecular Chemistry","volume":" ","pages":""},"PeriodicalIF":2.9000,"publicationDate":"2024-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Rhodium(III)-catalyzed direct C-H activation of 2-aryl-3<i>H</i>-indoles: a strategy for 4-heteroaryl pyrazole synthesis.\",\"authors\":\"Zi Yang, Ji Luo, Wenbo Zhang, Jieni Lei, Chaoshui Liu, Yaqian Li\",\"doi\":\"10.1039/d4ob01655f\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>A novel protocol for synthesizing 4-heteroaryl pyrazoles from readily available 2-aryl-3<i>H</i>-indoles and diazopyrazolones through the rhodium(III)-catalyzed C-H bond activation has been achieved. This redox-neutral strategy features powerful reactivity, tolerates various functional groups, and proceeds with moderate yields under mild reaction conditions.</p>\",\"PeriodicalId\":96,\"journal\":{\"name\":\"Organic & Biomolecular Chemistry\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":2.9000,\"publicationDate\":\"2024-11-27\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Organic & Biomolecular Chemistry\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://doi.org/10.1039/d4ob01655f\",\"RegionNum\":3,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CHEMISTRY, ORGANIC\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Organic & Biomolecular Chemistry","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.1039/d4ob01655f","RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, ORGANIC","Score":null,"Total":0}
Rhodium(III)-catalyzed direct C-H activation of 2-aryl-3H-indoles: a strategy for 4-heteroaryl pyrazole synthesis.
A novel protocol for synthesizing 4-heteroaryl pyrazoles from readily available 2-aryl-3H-indoles and diazopyrazolones through the rhodium(III)-catalyzed C-H bond activation has been achieved. This redox-neutral strategy features powerful reactivity, tolerates various functional groups, and proceeds with moderate yields under mild reaction conditions.
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
