临床环境中的耐多药铜绿假单胞菌:耐药机制与治疗策略综述》。

IF 3.3 3区 医学 Q2 MICROBIOLOGY Pathogens Pub Date : 2024-11-07 DOI:10.3390/pathogens13110975
Beth Schwartz, Katherine Klamer, Justin Zimmerman, Pramodini B Kale-Pradhan, Ashish Bhargava
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引用次数: 0

摘要

由于铜绿假单胞菌的高死亡率和耐药性,它正引起临床医生越来越多的关注。这种细菌是各种感染的罪魁祸首,尤其是在医院环境中,影响着一些最脆弱的病人。铜绿假单胞菌通过多种机制产生耐药性,使治疗面临挑战。诊断技术在不断发展,快速检测系统可在 4-6 小时内提供结果。新的抗菌药物也在不断开发,为这些复杂的临床决策提供了潜在的解决方案。本文综述了铜绿假单胞菌的流行病学、高危人群、耐药机制以及诊断和治疗方案。
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Multidrug Resistant Pseudomonas aeruginosa in Clinical Settings: A Review of Resistance Mechanisms and Treatment Strategies.

Pseudomonas aeruginosa is causing increasing concern among clinicians due to its high mortality and resistance rates. This bacterium is responsible for various infections, especially in hospital settings, affecting some of the most vulnerable patients. Pseudomonas aeruginosa has developed resistance through multiple mechanisms, making treatment challenging. Diagnostic techniques are evolving, with rapid testing systems providing results within 4-6 h. New antimicrobial agents are continuously being developed, offering potential solutions to these complex clinical decisions. This article provides a review of the epidemiology, at-risk populations, resistance mechanisms, and diagnostic and treatment options for Pseudomonas aeruginosa.

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来源期刊
Pathogens
Pathogens Medicine-Immunology and Allergy
CiteScore
6.40
自引率
8.10%
发文量
1285
审稿时长
17.75 days
期刊介绍: Pathogens (ISSN 2076-0817) publishes reviews, regular research papers and short notes on all aspects of pathogens and pathogen-host interactions. There is no restriction on the length of the papers. Our aim is to encourage scientists to publish their experimental and theoretical research in as much detail as possible. Full experimental and/or methodical details must be provided for research articles.
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