一个长期观察到的奥美沙坦相关性胃炎病例

IF 1 4区医学 Q3 MEDICINE, GENERAL & INTERNAL Internal Medicine Pub Date : 2024-11-28 DOI:10.2169/internalmedicine.4551-24

Mizuho Fujisawa, Tetsuya Yoshizaki, Satoshi Urakami, Risa Ashizaki, Eri Nishikawa, Hiroshi Tanabe, Shinya Hoki, Ryosuke Ishida, Hitomi Hori, Chise Ueda, Hirofumi Abe, Madoka Takao, Yoshinori Morita, Takashi Toyonaga, Yuzo Kodama

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引用次数: 0

摘要

一位服用奥美沙坦 7 年的 61 岁女性主诉上腹痛、腹泻、食欲不振和体重下降。食管胃十二指肠镜检查发现胃和十二指肠粘膜粗糙、糜烂。内镜活检未能确定粘膜病变的原因。小肠胶囊内镜检查发现小肠绒毛萎缩，这让人怀疑是奥美沙坦相关的芽胞样肠病和胃炎。停用奥美沙坦后，症状和胃黏膜检查结果均有所改善。最终确诊为奥美沙坦相关性胃炎。因上消化道症状而服用奥美沙坦的患者应考虑奥美沙坦相关性胃炎。

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A Case of Olmesartan-associated Gastritis Observed Over Time.

A 61-year-old woman who had been taking olmesartan for 7 years complained of epigastric pain, diarrhea, loss of appetite, and weight loss. Esophagogastroduodenoscopy revealed roughened mucosa and erosions in the stomach and duodenum. An endoscopic biopsy failed to identify the cause of the mucosal disorder. Small-bowel capsule endoscopy revealed villous atrophy in the small bowel, which led to suspicion of olmesartan-associated sprue-like enteropathy and gastritis. After the discontinuation of olmesartan, the symptoms and gastric mucosal findings improved. A final diagnosis of olmesartan-associated gastritis was confirmed. Olmesartan-associated gastritis should be considered in patients taking olmesartan for upper gastrointestinal symptoms.

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来源期刊

Internal Medicine 医学-医学：内科

CiteScore

1.90

自引率

8.30%

发文量

审稿时长

2.2 months

期刊介绍： Internal Medicine is an open-access online only journal published monthly by the Japanese Society of Internal Medicine. Articles must be prepared in accordance with "The Uniform Requirements for Manuscripts Submitted to Biomedical Journals (see Annals of Internal Medicine 108: 258-265, 1988), must be contributed solely to the Internal Medicine, and become the property of the Japanese Society of Internal Medicine. Statements contained therein are the responsibility of the author(s). The Society reserves copyright and renewal on all published material and such material may not be reproduced in any form without the written permission of the Society.