Ashlyn Runk, Meryl A Butters, Andrea L Rosso, Tamara Dubowitz, Wendy M Troxel, Juleen Rodakowski, Tiffany L Gary-Webb, Ann Haas, Bonnie Ghosh-Dastidar, Andrea M Weinstein
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We examined the predictive validity of the PASS shopping, medication management, and information retrieval subtests and the ECog-12 to dichotomize cognitive groups.</p><p><strong>Results: </strong>Performance on all PASS subtests (all <i>p</i>'s < .05) differed between cognitive groups, but not ECog-12 (<i>p</i> = 0.17). 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引用次数: 0
摘要
简介:我们研究了自理能力表现评估(PASS)和日常认知量表-12(ECog-12)是否将以黑人为主的成年人样本中的认知群体二分法:246 名居住在社区的成年人(95% 为黑人,年龄在 50 岁以上)完成了认知测试、PASS 和 ECog。认知障碍组别(可能有认知障碍与不可能有认知障碍)是根据 "改良小型精神状态检查"(Mini-Mental State Examination)的成绩确定的。我们研究了 PASS 购物、药物管理和信息检索子测试以及 ECog-12 的预测有效性,以二分认知障碍组别:所有 PASS 次测试的成绩(所有 p 的 p = 0.17)。只有 PASS 购物和药物管理在确定认知组别方面具有良好的可靠性(曲线下面积(AUC)均为 0.74):讨论:PASS购物和药物管理在区分认知状况组别时表现出足够的预测有效性,而PASS信息检索和ECog-12则没有:基于表现的评估是评估功能衰退的重要工具。大多数基于表现的测量方法都是在同质样本中开发的,很少有研究在其他种族和民族人群中验证这些测量方法。
Everyday functioning as a predictor of cognitive status in a group of community-dwelling, predominantly Black adults.
Introduction: We examined whether the Performance Assessment of Self-Care Skills (PASS) and Everyday Cognition Scale-12 (ECog-12) dichotomized cognitive groups in a sample of predominantly Black adults.
Methods: Two hundred forty-six community-dwelling adults (95% Black, age 50+) completed cognitive testing, the PASS, and the ECog. Cognitive groups (probable vs unlikely cognitive impairment) were determined by performance on the Modified Mini-Mental State Examination. We examined the predictive validity of the PASS shopping, medication management, and information retrieval subtests and the ECog-12 to dichotomize cognitive groups.
Results: Performance on all PASS subtests (all p's < .05) differed between cognitive groups, but not ECog-12 (p = 0.17). Only the PASS shopping and medication management had good reliability for determining cognitive group (areas under the curve (AUCs) of .74 each).
Discussion: PASS shopping and medication management exhibited adequate predictive validity when distinguished between cognitive status groups, whereas the PASS information retrieval and ECog-12 did not.
Highlights: Mild functional decline is a core diagnostic criterion for cognitive impairment.Performance-based assessments are a valuable tool for assessing functional decline.Most performance-based measures were developed using homogenous samples.Few studies have validated these measures in other racial and ethnic populations.
期刊介绍:
Alzheimer''s & Dementia: Diagnosis, Assessment & Disease Monitoring (DADM) is an open access, peer-reviewed, journal from the Alzheimer''s Association® that will publish new research that reports the discovery, development and validation of instruments, technologies, algorithms, and innovative processes. Papers will cover a range of topics interested in the early and accurate detection of individuals with memory complaints and/or among asymptomatic individuals at elevated risk for various forms of memory disorders. The expectation for published papers will be to translate fundamental knowledge about the neurobiology of the disease into practical reports that describe both the conceptual and methodological aspects of the submitted scientific inquiry. Published topics will explore the development of biomarkers, surrogate markers, and conceptual/methodological challenges. Publication priority will be given to papers that 1) describe putative surrogate markers that accurately track disease progression, 2) biomarkers that fulfill international regulatory requirements, 3) reports from large, well-characterized population-based cohorts that comprise the heterogeneity and diversity of asymptomatic individuals and 4) algorithmic development that considers multi-marker arrays (e.g., integrated-omics, genetics, biofluids, imaging, etc.) and advanced computational analytics and technologies.