正颌手术中恶性高热1例。

Yue Li, Jie Lin, Wei Luo, Kai Luo, Lin Luo
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引用次数: 0

摘要

恶性高热是一种罕见的危及生命的高热反应,发生在全身麻醉期间,术前诊断困难。在大多数报告的病例中,恶性高热的最终诊断最终是在高热发作后通过基因检测确认的。丹曲林是唯一能改善恶性高热治疗结果的特效药。在这项工作中,我们报告了一例恶性高热,发生在正颌手术。由于丹曲林的及时识别和特异性治疗,恶性高热得以成功逆转,术后仅观察到肌红蛋白和肌酸激酶的轻微升高。
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Malignant hyperthermia during orthognathic surgery: a case report.

Malignant hyperthermia is a rare life-threatening hyperthermic reaction that occurs during general anesthesia and is difficult to diagnose preoperatively. In most reported cases, final diagnoses of malignant hyperthermia were eventually confirmed by genetic testing after the episodes of hyperthermia. Dantrolene is the only specific medicine with improved treatment outcomes for malignant hyperthermia. In this work, we reported a case of malignant hyperthermia that occurred during orthognathic surgery. Malignant hyperthermia was successfully reversed because of the prompt recognition and specific treatment of dantrolene, and only slight increases in myoglobin and creatine kinase were observed postoperatively.

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