基于生物标志物筛选中/高风险MGUS患者症状前AL淀粉样变性的可行性

IF 10.1 1区医学 Q1 HEMATOLOGY American Journal of Hematology Pub Date : 2024-12-03 DOI:10.1002/ajh.27545

Silvia Mangiacavalli, Paolo Milani, Claudio Salvatore Cartia, Marzia Varettoni, Michele Palumbo, Marco Basset, Valeria Masoni, Mario Nuvolone, Andrea Foli, Virginia Valeria Ferretti, Giampaolo Merlini, Luca Arcaini, Giovanni Palladini

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引用次数: 0

摘要

基于生物标志物的筛查能够在中/高风险MGUS患者中早期发现AL淀粉样变。我们的研究表明，通过生物标志物纵向监测识别症状前AL可以早期治疗，导致显著的器官功能恢复。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Feasibility of a Biomarker-Based Screening for Pre-Symptomatic AL Amyloidosis in Patients With Intermediate/High-Risk MGUS

Biomarker-based screening enables early detection of AL amyloidosis in intermediate/high-risk MGUS patients. Our study shows that identifying pre-symptomatic AL through biomarker longitudinal monitoring allows early treatment, leading to significant organ function recovery.

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来源期刊

American Journal of Hematology 医学-血液学

CiteScore

15.70

自引率

3.90%

发文量

363

审稿时长

3-6 weeks

期刊介绍： The American Journal of Hematology offers extensive coverage of experimental and clinical aspects of blood diseases in humans and animal models. The journal publishes original contributions in both non-malignant and malignant hematological diseases, encompassing clinical and basic studies in areas such as hemostasis, thrombosis, immunology, blood banking, and stem cell biology. Clinical translational reports highlighting innovative therapeutic approaches for the diagnosis and treatment of hematological diseases are actively encouraged.The American Journal of Hematology features regular original laboratory and clinical research articles, brief research reports, critical reviews, images in hematology, as well as letters and correspondence.