颅内大叶性生殖细胞瘤表现为难治性高钠血症。

IF 1.3 4区 医学 Q4 CLINICAL NEUROLOGY Child's Nervous System Pub Date : 2024-12-03 DOI:10.1007/s00381-024-06675-3
Mahak Sipani, Gyani Jail Singh Birua, Abhinith Shashidhar, A Arivazhagan, Shilpa Rao, Jitender Saini
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引用次数: 0

摘要

中枢神经系统生殖细胞肿瘤最常见于中线结构。偏心生殖细胞瘤是罕见的,但可以发现在基底节区,叶,脑干,和颅穹窿。我们报告一个14岁的男孩,他表现出明显的尿崩症症状和体征,影像学诊断为左额叶高级胶质瘤。组织病理学证实为生殖细胞瘤。术后患者高钠血症消退,单剂量0.1 mg去氨加压素片维持正常钠稳态。本文报告一例罕见的偏心中枢神经系统生殖细胞瘤的年轻男性患者表现为尿崩症,没有任何明显的鞍上或鞍上受累。
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Intracranial lobar germinoma presenting with refractory hypernatremia.

Central nervous system germ cell tumours are most commonly seen in the midline structures. Eccentric germinomas are rare but can be found in the basal ganglia, lobar, brainstem, and cranial vault. We present a 14-year-old boy who presented with signs and symptoms of overt diabetes insipidus and a radiological diagnosis of left frontal high-grade glioma. Confirmative histopathology revealed germinoma. The patient had a resolution of hypernatremia post-surgery and maintained normal sodium homeostasis on a single dose of 0.1 mg of tablet desmopressin. This paper showcases a rare case of an eccentric central nervous system germinoma in a young male patient presenting with Diabetes Insipidus without any apparent sellar or suprasellar involvement.

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来源期刊
Child's Nervous System
Child's Nervous System 医学-临床神经学
CiteScore
3.00
自引率
7.10%
发文量
322
审稿时长
3 months
期刊介绍: The journal has been expanded to encompass all aspects of pediatric neurosciences concerning the developmental and acquired abnormalities of the nervous system and its coverings, functional disorders, epilepsy, spasticity, basic and clinical neuro-oncology, rehabilitation and trauma. Global pediatric neurosurgery is an additional field of interest that will be considered for publication in the journal.
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