银屑病关节炎患者的跨学科治疗方法:一项前瞻性单中心队列研究

IF 3.3 3区 医学 Q2 PHARMACOLOGY & PHARMACY Therapeutic Advances in Chronic Disease Pub Date : 2024-11-28 eCollection Date: 2024-01-01 DOI:10.1177/20406223241293698
Georg Gross, Christian Lull, Jan Alwin von Ahnen, Mara Blauth, Johanna Schwaan, Victor Olsavszky, Astrid Schmieder, Jan Leipe
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引用次数: 0

摘要

背景:银屑病关节炎(Psoriatic arthritis, PsA)是一种慢性全身性炎症性疾病,影响多达30%的银屑病患者。诊断和治疗可以通过实施跨学科皮肤风湿病会诊(IDRC)来改善。目的:本研究旨在评估面对面的IDRC,包括皮肤科医生和风湿病学家在一次就诊中评估患者对PsA患者疾病活动性和负担的影响。设计:前瞻性、单中心、队列研究。方法:纳入202例银屑病患者,其中115例伴有银屑病和肌肉骨骼症状的患者接受了IDRC。评估疾病表现、合并症以及客观和主观疾病活动性评分。结果:在参与者中,56人被诊断为明确的PsA,而其余146人患有牛皮癣。累及指甲与轴向PsA相关(优势比4.11;95% ci 1.22-13.82;p = 0.02)。PsA患者通常经历较长的诊断时间(平均187周),并有显著的社会心理负担(平均医院焦虑和抑郁指数量表[HADS]-焦虑评分为7.66,平均HADS-抑郁评分为5.63)。在IDRC之后,客观和主观疾病参数都有所改善,与IDRC之前相比,患者需要较少的时间与医疗保健专业人员进行咨询。结论:IDRC方法可有效加快和优化银屑病合并肌肉骨骼症状患者的诊断和治疗。
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Interdisciplinary approach to patients with psoriatic arthritis: a prospective, single-center cohort study.

Background: Psoriatic arthritis (PsA) is a chronic systemic inflammatory disease that affects up to 30% of patients with psoriasis. Diagnosis and treatment could be improved by implementing an interdisciplinary dermatological-rheumatological consultation (IDRC).

Objectives: This study aimed to assess the effect of a face-to-face IDRC involving both a dermatologist and a rheumatologist evaluating patients in a single visit, on disease activity and burden in patients with PsA.

Design: Prospective, single-center, cohort study.

Methods: 202 patients with psoriasis were enrolled, among whom 115 individuals with psoriasis and musculoskeletal symptoms underwent an IDRC. Disease manifestations, comorbidities, and both objective and subjective disease activity scores were evaluated.

Results: Out of the participants, 56 were diagnosed with definite PsA, while the remaining 146 had psoriasis. Nail involvement was associated with axial PsA (odds ratio 4.11; 95% CI 1.22-13.82; p = 0.02). Patients with PsA often experienced a prolonged time to diagnosis (mean 187 weeks) and had a significant psychosocial burden (mean Hospital Anxiety and Depression Index Scale [HADS]-Anxiety score of 7.66 and mean HADS-Depression score of 5.63). Post-IDRC, both objective and subjective disease parameters showed improvement, and patients required less time for consultations with healthcare professionals compared to before the IDRC.

Conclusion: These findings suggest that an IDRC approach could effectively expedite and optimize the diagnosis and treatment of patients with psoriasis and musculoskeletal symptoms.

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来源期刊
Therapeutic Advances in Chronic Disease
Therapeutic Advances in Chronic Disease Medicine-Medicine (miscellaneous)
CiteScore
6.20
自引率
0.00%
发文量
108
审稿时长
12 weeks
期刊介绍: Therapeutic Advances in Chronic Disease publishes the highest quality peer-reviewed research, reviews and scholarly comment in the drug treatment of all chronic diseases. The journal has a strong clinical and pharmacological focus and is aimed at clinicians and researchers involved in the medical treatment of chronic disease, providing a forum in print and online for publishing the highest quality articles in this area.
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