对经营性血库困境的再思考:跳出“盒子”的血液储运评价。

Scott B Hughey, Joshua Kotler, Adam Brust, Jacob H Cole, Yuki Itani, Anna Hughey, Takashi Nagata, Kyle Checchi
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引用次数: 0

摘要

背景:输血在现代创伤护理中至关重要。然而,在严峻的军事和灾难医疗环境中,获得健全血库的不可靠途径仍然具有挑战性。储存的全血及其成分有严格的冷藏指南;任何导致血液制品偏离其目标温度的冷链储存责任都会影响患者的安全。在一个典型的血库中,冷藏需要大型的专用设备。可移动的、电池供电的设备是可用的,但它们的电池寿命有限。本研究评估了使用被动冷却设备(市售食品冷却器)储存血液成分的可能性。方法:使用市售的45升容量冷却器。生理盐水袋(500mL)预冷至1-6℃,置于冷却器中。在每个盐水袋旁边的冷却器中放置一个温度计,测量每次试验期间冷却器的温度。主要结果是充分冷藏的时间(1 - 6°C)。结果:共4次试验,每次持续168小时。试验1-3维持目标温度范围为142小时,试验4维持目标温度范围为78小时。结论:在严峻、灾害和军事作战环境中,使用市售冷却器和冰的被动制冷是传统血液储存方案的可行替代方案。进一步的研究应探讨使用这种技术在定期添加冰的情况下延长血液储存。
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Rethinking the Operational Blood Bank Dilemma: Out of the "Box" Blood Storage and Transportation Evaluation.

Background: Blood transfusion is critical in modern trauma care. However, unreliable access to robust blood banking in austere military and disaster medicine settings remains challenging. Stored whole blood and components have strict refrigeration guidelines; any cold-chain storage liability that results in blood products deviating from their target temperatures affects patient safety. Refrigeration in a typical blood bank requires large, specialized devices. Transportable, battery-operated devices are available, but they have limited battery life. This study evaluated the possibility of using passively cooled devices (commercially available food coolers) to store blood components.

Methods: A commercially available 45-liter capacity cooler was used. Saline bags (500mL) were precooled to 1-6°C and placed in the cooler. A thermometer placed in the cooler adjacent to each saline bag measured the cooler temperature throughout each trial. The primary outcome was the hours of adequate refrigeration (between 1 and 6°C).

Results: There were four trials, each lasting 168 hours. Trials 1-3 maintained the goal temperature range for >142 hours, while trial 4 maintained temperature range for 78 hours.

Conclusion: Passive refrigeration using commercially available coolers and ice is a viable alternative to traditional blood storage solutions in austere, disaster, and military operational environments. Further studies should investigate prolonged blood storage using this technique with the periodic addition of ice.

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来源期刊
CiteScore
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发文量
91
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