语言紊乱的潜在机制与精神病理的特定维度有关

Isaac Fradkin, Rick A. Adams, Noam Siegelman, Rani Moran, Raymond J. Dolan
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摘要

可理解的沟通对社会功能和福祉至关重要。在精神病理学中,不连贯的话语被认为反映了混乱的思维,这通常与精神障碍有关。然而,人们并不会把想到的一切都表达出来,这使得从话语到思想底层结构的推断具有挑战性。事实上,在语言输出不连贯的情况下,一系列的精神病理都与自我报告的混乱思维有关。在这里,我们将自然语言处理和自由联想的计算模型结合起来,详细说明了在精神病理不同维度的大样本参与者中,无组织思维和语言连贯之间的关系。我们的方法使我们能够区分无组织思维、不受抑制的思想表达和深思熟虑的创造力。我们发现了缺乏监管和过度监管的无组织思维的证据,这与精神病理学的两个特定维度有关:自我报告的怪癖和多疑。总的来说,这些结果强调了通过分析潜在维度的行为和精神病理学所提供的理论进展。本研究利用自然语言处理和计算模型,发现无组织思维、通过表达解除抑制和刻意创造与精神病理学的怪癖和怀疑维度存在差异。
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Latent mechanisms of language disorganization relate to specific dimensions of psychopathology
Comprehensible communication is critical for social functioning and well-being. In psychopathology, incoherent discourse is assumed to reflect disorganized thinking, which is classically linked to psychotic disorders. However, people do not express everything that comes to mind, rendering inferences from discourse to the underlying structure of thought challenging. Indeed, a range of psychopathologies are linked to self-reported disorganized thinking in the absence of language output incoherence. Here we combine natural language processing and computational modeling of free association to detail the relationship between disorganized thinking and language (in)coherence in a large sample of participants varying across different dimensions of psychopathology. Our approach allowed us to differentiate between disorganized thinking, disinhibited thought expression and deliberate creativity. We find evidence for both under-regulated and over-regulated disorganized thinking, which relate to two specific dimensions of psychopathology: self-reported eccentricity and suspiciousness. Broadly, these results underscore the theoretical progress afforded by analyzing latent dimensions underlying behavior and psychopathology. Using natural language processing and computational modeling, this study finds distinctions among disorganized thinking, disinhibition through expression and deliberate creativity, which are differentially associated with eccentricity and suspiciousness dimensions of psychopathology.
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