埃塞俄比亚西南部2型糖尿病患者的血糖控制及相关因素:一项前瞻性观察研究

IF 2.8 3区 医学 Q3 ENDOCRINOLOGY & METABOLISM BMC Endocrine Disorders Pub Date : 2024-12-05 DOI:10.1186/s12902-024-01795-y
Aster Wakjira Garedo, Gorfineh Teshome Tesfaye, Rahel Tamrat, Evelien Wynendaele
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引用次数: 0

摘要

背景:糖尿病是一种以高血糖和葡萄糖不耐受为特征的已知综合征,在世界范围内正以惊人的速度增加。全世界有超过5亿人患有糖尿病,其中大多数生活在低收入和中等收入国家。血糖控制不良是2型糖尿病患者的一个公共健康问题。血糖控制和识别与血糖控制不良相关的因素可以帮助医疗保健提供者设计方案,改善血糖控制和为患者提供的服务质量。目的:本研究旨在评估埃塞俄比亚西南部Jimma医疗中心2型糖尿病患者的血糖控制水平及相关因素。方法:本研究以机构为基础,对吉马医疗中心糖尿病门诊的420例2型糖尿病患者进行前瞻性观察研究。使用预先测试的结构化访谈者管理的问卷来收集数据,并使用检查表来评估患者文件。数据采用SPSS 26进行分析。使用二元逻辑回归研究与血糖控制不良相关的变量。p值小于0.05的变量被认为具有统计学意义。结果:420例2型糖尿病患者随访6个月,其中女性220例(52.38%)。参与者的中位年龄为54岁(IQR = 40-60岁)。受访者空腹血糖不控制的比例为58.1%。性(AOR = 2.576, 95% CI [2.80 - -11.479], P = 0.001),年龄(≥60岁)(优势比= 2.024,95% CI [1.794 - -4.646], P = 0.002),糖尿病病程> 10年(优势比= 3.036,95% CI [2.616 - -8.306], P = 0.003), 2型糖尿病胰岛素+口服抗糖尿病的(全尺寸)(优势比= 2.08,95% CI [298 - 3.918], P = 0.004),肥胖(优势比= 2.18,95% CI [(1.218 - -4.218)], P = 0.003),糖尿病并发症(优势比= 3.193,95% CI [2.324 - -6.05], P = 0.002)和不良的自我照顾行为(优势比= 3.034,95% CI (5.821 - -7.02),P = 0.005)与血糖控制不良显著相关。结论:吉马医疗中心血糖控制不良的发生率较高。基于这些发现,医疗保健提供者提供的教学和咨询应侧重于改善糖尿病自我保健活动、减轻体重和糖尿病并发症,以实现良好的血糖控制。临床试验号:不适用。
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Glycemic control and associated factors in patients with type 2 diabetes in Southwest Ethiopia: a prospective observational study.

Background: Diabetes, a known syndrome marked by hyperglycemia and glucose intolerance, is increasing at an alarming rate worldwide. Over half a billion people worldwide have DM, and most live in low- and middle-income countries. Poor glycemic control is a public health concern in type 2 diabetes mellitus. Glycemic control and identifying factors associated with poor glycemic control can help healthcare providers design programs that improve glycemic control and the quality of services provided to patients.

Objectives: This study was designed to assess the level of glycemic control and associated factors in patients with type 2 diabetes in Jimma Medical Center, Southwest Ethiopia.

Methods: This institution-based prospective observational study was conducted among 420 patients with type 2 diabetes at Jimma Medical Center's diabetic clinics. A pretested structured interviewer-administered questionnaire was used to collect data, and a checklist was used to assess patient documents. The data were analyzed using SPSS version 26. The variables linked to poor glycemic control were investigated using binary logistic regression. Variables with p values less than 0.05 were considered statistically significant.

Results: Six-month follow-ups were conducted among 420 patients with type 2 diabetes, among whom 220 (52.38%) were women. The median age of the participants was 54(IQR = 40-60 years old). The proportion of respondents with uncontrolled fasting blood glucose was 58.1%. Sex (AOR = 2.576, 95% CI [2.80-11.479], P = 0.001), age(≥ 60) (AOR = 2.024, 95% CI [1.794-4.646], P = 0.002), diabetes duration > 10 years (AOR = 3.036, 95% CI [2.616-8.306], P = 0.003), type 2 diabetes mellitus on insulin + oral antidiabetic (OADs) (AOR = 2.08, 95% CI [298-3.918], P = 0.004), obesity (AOR = 2.18, 95% CI [(1.218-4.218)], P = 0.003), diabetic complications (AOR = 3.193, 95% CI [2.324-6.05], p = 0.002) and poor self-care practices (AOR = 3.034, 95% CI [5.821-7.02], P = 0.005) were found to be significantly associated with poor glycemic control.

Conclusion: At the Jimma Medical Center, the prevalence of poor glycemic control was high. Based on these findings, teaching and counseling provided by healthcare providers should focus on improving diabetes self-care activities, weight reduction, and diabetic complications to achieve good glycemic control.

Clinical trial number: Not applicable.

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来源期刊
BMC Endocrine Disorders
BMC Endocrine Disorders ENDOCRINOLOGY & METABOLISM-
CiteScore
4.40
自引率
0.00%
发文量
280
审稿时长
>12 weeks
期刊介绍: BMC Endocrine Disorders is an open access, peer-reviewed journal that considers articles on all aspects of the prevention, diagnosis and management of endocrine disorders, as well as related molecular genetics, pathophysiology, and epidemiology.
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