单独文章:预防和管理靶向治疗相关皮肤不良事件的USCOM IV算法。

IF 1.5 4区 医学 Q3 DERMATOLOGY Journal of Drugs in Dermatology Pub Date : 2024-12-01 DOI:10.36849/jdd.43661
Jonathan Leventhal, Ana Sofia Acosta Madiedo, Anneke Andriessen, Jennifer N Choi, Alice Ho, Beth McLellan, Edith Mitchell, Mario Lacouture
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引用次数: 0

摘要

前言:靶向治疗改善了各种类型癌症的临床结果。然而,它们的使用与影响生活质量和一致性治疗的皮肤不良事件有关。目的:美国皮肤肿瘤皮肤病管理(USCOM)多学科指导算法,用于预防和管理皮肤靶向治疗相关不良事件,为癌症患者和幸存者提供实用建议。方法:USCOM顾问委员会(小组)确定了6种与靶向治疗相关的常见皮肤不良事件。根据文献检索的结果、临床专业知识和意见,制定了预防和管理的实用建议。结果:痤疮样皮疹、瘙痒、干燥、甲沟炎、色素沉着、手足皮肤反应被选为常见的靶向治疗相关皮肤不良事件。该小组提供了预防和治疗这些皮肤状况的实际步骤。结论:USCOM多学科指导算法适用于接受靶向治疗的肿瘤患者的医疗保健提供者。皮肤靶向治疗相关的不良事件需要及时准确的诊断和多学科管理,包括皮肤科医生和肿瘤学团队,限制癌症治疗的中断,优化生活质量和治疗结果。皮肤医学杂志,2024;23:12(增刊1):53 -14。
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INDIVIDUAL ARTICLE: USCOM IV Algorithm for the Prevention and Management of Targeted Therapy-Related Cutaneous Adverse Events.

Introduction: Targeted therapy has improved clinical outcomes for various types of cancer. However, their use is associated with dermatologic adverse events that impact quality of life and consistent therapies.

Objectives: The US Cutaneous Oncodermatology Management (USCOM) multidisciplinary-guided algorithm for preventing and managing cutaneous targeted therapy-related adverse events provides practical recommendations for cancer patients and survivors.

Methods: The USCOM advisory board (panel) identified 6 commonly occurring cutaneous adverse events associated with targeted therapies. Practical recommendations for prevention and management were developed based on the results of a literature search, clinical expertise, and opinion.

Results: Acneiform rash, pruritus, xerosis, paronychia, hyperpigmentation, and hand-foot skin reaction were selected as common targeted therapy-related cutaneous adverse events. The panel provides practical steps for preventing and treating these cutaneous conditions.

Conclusions: The USCOM multidisciplinary-guided algorithm is for healthcare providers treating oncology patients receiving targeted therapies. Cutaneous targeted therapy-related adverse events necessitate prompt and accurate diagnosis and multidisciplinary management that includes a dermatologist and the oncologic team, limiting disruption of cancer treatment and optimizing quality of life and treatment outcomes. J Drugs Dermatol. 2024;23:12(Suppl 1):s3-14.

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来源期刊
CiteScore
2.20
自引率
13.30%
发文量
289
审稿时长
3-6 weeks
期刊介绍: The Journal of Drugs in Dermatology (JDD) is a peer-reviewed publication indexed with MEDLINE®/PubMed® that was founded by the renowned Dr. Perry Robins MD. Founded in 2002, it offers one of the fastest routes to disseminate dermatologic information and is considered the fastest growing publication in dermatology. We present original articles, award-winning case reports, and timely features pertaining to new methods, techniques, drug therapy, and devices in dermatology that provide readers with peer reviewed content of the utmost quality. Our high standards of content are maintained through a balanced, peer-review process. Articles are reviewed by an International Editorial Board of over 160 renowned experts.
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