80岁以上前列腺癌患者预后的研究

Kodai Hattahara, Yuki Hashimoto, Masayuki Uegaki, Koji Nishizawa, Toru Yoshida
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引用次数: 0

摘要

随着日本人口的老龄化,越来越多的老年前列腺癌患者需要治疗。然而,老年人经常有合并症,这使得前列腺癌患者的治疗决策变得困难。因此,我们调查了在本院诊断为前列腺癌的80岁及以上患者的前列腺癌死亡和危险因素。2011年1月至2018年12月在我院诊治的532例前列腺癌病例中,纳入90例。中位观察期为54个月,13例(14.4%)患者死于前列腺癌。总体5年癌症特异性生存率为86.7%,多因素分析中M1(47.1%)和GS≥9(71.9%)为显著危险因素。转移性前列腺癌患者,即使是年龄超过80岁的患者,在向患者和家属解释前列腺癌死亡的几率并不低后,也应谨慎开始治疗。即使在局限性前列腺癌患者中,45名高危前列腺癌患者中有4名(8.9%)死于前列腺癌,这表明根据患者的预期寿命,根治性治疗是一种选择。
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[A Study of the Prognosis of Prostate Cancer Patients Over 80 Years of Age].

With the ageing of the population in Japan, an increasing number of elderly prostate cancer patients will require treatment. However, the elderly often have comorbidities, which can make treatment decisions for prostate cancer patients difficult. Therefore, we investigated prostate cancer deaths and risk factors among patients aged 80 years or older at diagnosis of prostate cancer at our hospital. Of 532 prostate cancer cases diagnosed and treated at our hospital between January2011 and December 2018, 90 cases were included. The median observation period was 54 months and 13 (14.4%) patients died of prostate cancer. The overall 5-year cancer-specific survival rate was 86.7%, with M1 (47.1%) and GS≥9 (71.9%) as significant risk factors on multivariate analysis. Patients with metastatic prostate cancer, even those older than 80 years, should be cautiously started on treatment after explaining to the patient and family that the chance of prostate cancer death is not low. Even in patients with localized prostate cancer, four out of 45 (8.9%) high-risk prostate cancer patients died of prostate cancer, suggesting that curative treatment is an option, depending on their life expectancy.

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来源期刊
Acta Urologica Japonica
Acta Urologica Japonica Medicine-Medicine (all)
CiteScore
0.20
自引率
0.00%
发文量
74
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