Vasavi G. , Vaddadi Vasudha Rani , Sreenu Ponnada , Jyothi S.
{"title":"利用MRI图像检测脑肿瘤的高效网络- dbnealexnet混合型。","authors":"Vasavi G. , Vaddadi Vasudha Rani , Sreenu Ponnada , Jyothi S.","doi":"10.1016/j.compbiolchem.2024.108279","DOIUrl":null,"url":null,"abstract":"<div><div>The rapid growth of abnormal cells in the brain presents a serious risk to the health of humans as it can result in death. Since these tumors have a varied range of shapes, sizes, and positions, identifying Brain Tumors (BTs) is challenging. Magnetic Resonance Images (MRI) are most utilized for identifying malignant tumors. This paper develops a new approach, named EfficientNet-Deep batch normalized eLUAlexnet (EfficientNet-DbneAlexnet) for detecting BTs. Firstly, the input MRI image is transmitted for image enhancement. Here, the image is enhanced by the Piecewise Linear Transformation (PLT). After this, skull stripping is carried out, which is performed by the Fuzzy Local Information C Means (FLICM). Following this, the tumor area in the image is segmented with the help of a Projective Adversarial Network (PAN). The segmented image is later applied to the feature extraction module, wherein features like textural and statistical features are extracted. Finally, the BT detection is accomplished using the developed EfficientNet-DbneAlexnet, which is created by assimilating EfficientNet and Deep batch normalized eLUAlexnet (DbneAlexnet). The results demonstrate that EfficientNet-DbneAlexnet obtained a sensitivity of 90.36 %, accuracy of 92.77 %, and specificity of 91.82 %.</div></div>","PeriodicalId":10616,"journal":{"name":"Computational Biology and Chemistry","volume":"115 ","pages":"Article 108279"},"PeriodicalIF":2.6000,"publicationDate":"2024-11-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"A hybrid EfficientNet-DbneAlexnet for brain tumor detection using MRI images\",\"authors\":\"Vasavi G. , Vaddadi Vasudha Rani , Sreenu Ponnada , Jyothi S.\",\"doi\":\"10.1016/j.compbiolchem.2024.108279\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>The rapid growth of abnormal cells in the brain presents a serious risk to the health of humans as it can result in death. Since these tumors have a varied range of shapes, sizes, and positions, identifying Brain Tumors (BTs) is challenging. Magnetic Resonance Images (MRI) are most utilized for identifying malignant tumors. This paper develops a new approach, named EfficientNet-Deep batch normalized eLUAlexnet (EfficientNet-DbneAlexnet) for detecting BTs. Firstly, the input MRI image is transmitted for image enhancement. Here, the image is enhanced by the Piecewise Linear Transformation (PLT). After this, skull stripping is carried out, which is performed by the Fuzzy Local Information C Means (FLICM). Following this, the tumor area in the image is segmented with the help of a Projective Adversarial Network (PAN). The segmented image is later applied to the feature extraction module, wherein features like textural and statistical features are extracted. Finally, the BT detection is accomplished using the developed EfficientNet-DbneAlexnet, which is created by assimilating EfficientNet and Deep batch normalized eLUAlexnet (DbneAlexnet). The results demonstrate that EfficientNet-DbneAlexnet obtained a sensitivity of 90.36 %, accuracy of 92.77 %, and specificity of 91.82 %.</div></div>\",\"PeriodicalId\":10616,\"journal\":{\"name\":\"Computational Biology and Chemistry\",\"volume\":\"115 \",\"pages\":\"Article 108279\"},\"PeriodicalIF\":2.6000,\"publicationDate\":\"2024-11-16\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Computational Biology and Chemistry\",\"FirstCategoryId\":\"99\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S1476927124002676\",\"RegionNum\":4,\"RegionCategory\":\"生物学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"BIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Computational Biology and Chemistry","FirstCategoryId":"99","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1476927124002676","RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"BIOLOGY","Score":null,"Total":0}
A hybrid EfficientNet-DbneAlexnet for brain tumor detection using MRI images
The rapid growth of abnormal cells in the brain presents a serious risk to the health of humans as it can result in death. Since these tumors have a varied range of shapes, sizes, and positions, identifying Brain Tumors (BTs) is challenging. Magnetic Resonance Images (MRI) are most utilized for identifying malignant tumors. This paper develops a new approach, named EfficientNet-Deep batch normalized eLUAlexnet (EfficientNet-DbneAlexnet) for detecting BTs. Firstly, the input MRI image is transmitted for image enhancement. Here, the image is enhanced by the Piecewise Linear Transformation (PLT). After this, skull stripping is carried out, which is performed by the Fuzzy Local Information C Means (FLICM). Following this, the tumor area in the image is segmented with the help of a Projective Adversarial Network (PAN). The segmented image is later applied to the feature extraction module, wherein features like textural and statistical features are extracted. Finally, the BT detection is accomplished using the developed EfficientNet-DbneAlexnet, which is created by assimilating EfficientNet and Deep batch normalized eLUAlexnet (DbneAlexnet). The results demonstrate that EfficientNet-DbneAlexnet obtained a sensitivity of 90.36 %, accuracy of 92.77 %, and specificity of 91.82 %.
期刊介绍:
Computational Biology and Chemistry publishes original research papers and review articles in all areas of computational life sciences. High quality research contributions with a major computational component in the areas of nucleic acid and protein sequence research, molecular evolution, molecular genetics (functional genomics and proteomics), theory and practice of either biology-specific or chemical-biology-specific modeling, and structural biology of nucleic acids and proteins are particularly welcome. Exceptionally high quality research work in bioinformatics, systems biology, ecology, computational pharmacology, metabolism, biomedical engineering, epidemiology, and statistical genetics will also be considered.
Given their inherent uncertainty, protein modeling and molecular docking studies should be thoroughly validated. In the absence of experimental results for validation, the use of molecular dynamics simulations along with detailed free energy calculations, for example, should be used as complementary techniques to support the major conclusions. Submissions of premature modeling exercises without additional biological insights will not be considered.
Review articles will generally be commissioned by the editors and should not be submitted to the journal without explicit invitation. However prospective authors are welcome to send a brief (one to three pages) synopsis, which will be evaluated by the editors.