缺血性胎盘疾病:流行病学及其对母婴健康的影响。

IF 1.4 4区 医学 Q3 OBSTETRICS & GYNECOLOGY Clinical obstetrics and gynecology Pub Date : 2025-03-01 Epub Date: 2024-12-06 DOI:10.1097/GRF.0000000000000914
Emily E Daggett, Cande V Ananth
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引用次数: 0

摘要

缺血性胎盘病(IPD)是一系列产科并发症,包括先兆子痫、胎盘早剥和胎儿生长受限,影响12%至15%的妊娠。导致这三种并发症的统一病理生理机制是子宫胎盘缺血,这是由母体子宫螺旋动脉生理转化不足(或失败)、内皮细胞功能障碍和氧化应激增加引起的。本文综述了IPD的相关文献,重点介绍了IPD的流行病学和危险因素,IPD对母体短期和长期并发症的影响,以及IPD与围产期、儿童期和后代长期并发症的关系。
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Ischemic Placental Disease: Epidemiology and Impact on Maternal and Offspring Health Along the Life Course.

Ischemic placental disease (IPD) is a constellation of obstetrical complications that include preeclampsia, placental abruption, and fetal growth restriction and affects 12% to 15% of pregnancies. The unifying pathophysiological mechanism that precedes all 3 complications is uteroplacental ischemia as a consequence of inadequate (or failure of) physiological transformation of the maternal uterine spiral arteries, endothelial cell dysfunction, and increased oxidative stress. This review summarizes the IPD literature, focusing on the epidemiology and risk factors, the effects of IPD on short and long-term maternal complications, and the association of IPD with perinatal, childhood, and long-term complications in offspring.

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来源期刊
CiteScore
2.70
自引率
0.00%
发文量
186
审稿时长
3 months
期刊介绍: Each issue of Clinical Obstetrics and Gynecology is a complete symposium on one or two timely topics of interest in obstetrics and gynecology. For each quarterly issue, two prominent guest editors solicit contributions on key clinical topics of interest to practicing physicians. Procedures, current clinical problems, medical and surgical treatments, and effective diagnostic aids are all carefully reviewed in original articles. The result is an instructive resource that dispenses trustworthy clinical guidance that enhances your understanding of key areas of your practice.
期刊最新文献
Menopause and Sexual Health: Hormones, Aging or Both? Persistent Genital Arousal Disorder/Genitopelvic Dysesthesia. Psychotherapy in Treating Female Sexual Dysfunction. Rare Pathologic Placenta Ultrasound Findings. Ischemic Placental Disease: Epidemiology and Impact on Maternal and Offspring Health Along the Life Course.
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