超声内镜和计算机断层扫描鉴别胰腺囊性肿瘤的有效性:单中心经验。

IF 1.4 4区 医学 Q4 GASTROENTEROLOGY & HEPATOLOGY Turkish Journal of Gastroenterology Pub Date : 2024-11-28 DOI:10.5152/tjg.2023.23492
Bengi Öztürk, Koray Ceyhan, Mehmet Bektaş
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引用次数: 0

摘要

背景/目的:影像学的进步导致胰腺囊肿诊断率上升。超声内镜(EUS)是胰腺囊肿诊断的重要手段之一。本研究的目的是确定胰腺囊肿的临床、实验室、生化、放射学和超声特征,并评估EUS和计算机断层扫描(CT)在区分肿瘤和非肿瘤囊肿方面的有效性。材料与方法:回顾性分析2010 - 2015年间在安卡拉大学医学院消化内科EUS实验室行EUS检查的CT诊断胰腺囊肿患者。比较大小、位置、数量和形态特征。通过eus引导细针抽吸(EUS-FNA)获得细胞学和生化检测样本。结果:研究组纳入212例患者。其中125例(59%)患者行EUS-FNA。其中,63例(52%)为肿瘤性,29例(24%)为非肿瘤性,29例(24%)缺乏亚组分析。CT鉴别肿瘤与非肿瘤囊肿的敏感性为82.1% [CI, 68.2% ~ 91.9%],特异性为61.1% (CI, 38.2% ~ 81%),诊断准确率为75.4%。EUS的敏感性为96.7% (CI, 90.2% ~ 99.4%),特异性为45.8% (CI, 27.1% ~ 65.4%),诊断准确率为82.3%。结论:超声内镜对胰腺囊肿鉴别是非肿瘤性囊肿的敏感性高于CT。虽然没有发现统计学意义,但该结果在临床上具有显著意义。此外,EUS在显示特定形态学特征方面显示出明显的优势,强调其作为评估胰腺囊性肿瘤的有价值的诊断工具的潜力。
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The Effectiveness of Endoscopic Ultrasonography and Computed Tomography in the Differentiation of Pancreatic Cystic Neoplasms: A Single-Center Experience.

Background/aims: Radiological imaging advancements have led to a rise in pancreatic cyst diagnoses. Apart from imaging modalities, endoscopic ultrasonography (EUS) is an important method in the diagnosis of pancreatic cysts. The aim of this study is to determine the clinical, laboratory, biochemical, radiological, and endosonographic features of pancreatic cysts and to assess the effectiveness of EUS and computed tomography (CT) in differentiating between neoplastic and nonneoplastic cysts.

Materials and methods: Patients with pancreatic cysts diagnosed by CT, who underwent EUS at the EUS Laboratory of Ankara University Faculty of Medicine, Gastroenterology Department, between 2010 and 2015, were retrospectively evaluated. Size, location, number, and morphological features were compared. Samples for cytology and biochemical tests were obtained through EUS-guided fine needle aspiration (EUS-FNA).

Results: The study group included 212 patients. Among them, 125 (59%) patients underwent EUS-FNA. Of these, 63 (52%) were neoplastic, 29 (24%) were nonneoplastic, and 29 (24%) lacked subgroup analysis. The sensitivity of CT in differentiating between neoplastic and nonneoplastic cysts was 82.1% [CI, 68.2%-91.9%], with a specificity of 61.1% (CI, 38.2%-81%) and diagnostic accuracy of 75.4%. Regarding EUS, the sensitivity was 96.7% (CI, 90.2%-99.4%), with a specificity of 45.8% (CI, 27.1%-65.4%) and diagnostic accuracy of 82.3%.

Conclusion: Endoscopic ultrasonography demonstrated enhanced sensitivity compared with CT in differentiating neoplastic from nonneoplastic pancreatic cysts. Although no statistical significance was found, this result can be considered clinically remarkable. In addition, EUS displayed distinct advantages in visualizing specific morphological features, emphasizing its potential as a valuable diagnostic tool in assessing pancreatic cystic neoplasms.

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来源期刊
Turkish Journal of Gastroenterology
Turkish Journal of Gastroenterology 医学-胃肠肝病学
CiteScore
1.90
自引率
0.00%
发文量
127
审稿时长
6 months
期刊介绍: The Turkish Journal of Gastroenterology (Turk J Gastroenterol) is the double-blind peer-reviewed, open access, international publication organ of the Turkish Society of Gastroenterology. The journal is a bimonthly publication, published on January, March, May, July, September, November and its publication language is English. The Turkish Journal of Gastroenterology aims to publish international at the highest clinical and scientific level on original issues of gastroenterology and hepatology. The journal publishes original papers, review articles, case reports and letters to the editor on clinical and experimental gastroenterology and hepatology.
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