重度脊柱侧凸的夜间低氧血症

B. Midgren , K. Petersson , L. Hansson , L. Eriksson , P. Airikkala , D. Elmqvist
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引用次数: 28

摘要

本文对13例重度胸侧凸患者的肺量测定与日间血气及睡眠时低氧血症的关系进行了研究。8例患者在睡眠期间出现低氧血症(平均Sao2<90%)。他们的特点是肺活量较低(30% vs 50%的预测,P<0.01),从坐姿到仰卧的肺活量下降更大(26% vs 7%的坐着的VC, P<0.05)。所有睡眠低氧血症患者白天均出现高碳酸血症。睡眠时Sao2的下降与经皮Pco2的增加有关,表明低通气是脊柱侧凸患者睡眠时低氧血症的主要机制。
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Nocturnal hypoxaemia in severe scoliosis

The relationship between spirometry and daytime blood gases on the one hand and hypoxaemia during sleep on the other was studied in 13 patients with severe thoracic scoliosis. Eight patients had hypoxaemia (mean Sao2<90%) during sleep. They were characterized by a lower vital capacity (30 versus 50% of predicted, P<0.01) and by a greater fall in vital capacity from sitting to supine (26 versus 7% of sitting VC, P<0.05). All patients with hypoxaemia during sleep were hypercapnic during the daytime. The fall in Sao2 with sleep was related to the increase in transcutaneous Pco2, indicating hypoventilation as the main mechanism behind hypoxaemia during sleep in scoliosis patients.

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