推进高光谱成像和机器学习工具在组织诊断中的临床应用:全面回顾。

IF 6.6 3区 医学 Q1 ENGINEERING, BIOMEDICAL APL Bioengineering Pub Date : 2024-12-06 eCollection Date: 2024-12-01 DOI:10.1063/5.0240444
Chun-Liang Lai, Riya Karmakar, Arvind Mukundan, Ragul Kumar Natarajan, Song-Cun Lu, Cheng-Yi Wang, Hsiang-Chen Wang
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引用次数: 0

摘要

高光谱成像(HSI)已成为医学诊断中一个明显的变革性仪器。本文旨在评价目前HSI在医疗应用中的进展和挑战。它具有多种医疗应用,如诊断糖尿病视网膜病变,帕金森病和阿尔茨海默病等神经退行性疾病,这说明了它在早期诊断,牙周病早期龋齿检测和皮肤病学通过检测皮肤癌的有效性。尽管取得了这些进展,但在各个方面都存在着限制其广泛临床应用的挑战。它有各种各样的限制,包括与HSI系统的复杂性相关的技术困难和需要专家培训,这可能成为其临床设置的缺点。本文涉及医疗应用中表达的潜在挑战以及克服这些限制的可能解决方案。本研究强调了在医疗应用方面使用HSI提供先进解决方案的成功公司,以表明对医疗诊断系统的高度兴趣,这些系统将机器学习ML和人工智能AI结合起来,以促进精确诊断和标准化临床工作流程。这一进展标志着HSI在实时临床评估中的进步可能性。总之,尽管HSI已被视为一种重要的先进医学成像工具,但解决其局限性和可能的解决方案需要更广泛的临床应用。
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Advancing hyperspectral imaging and machine learning tools toward clinical adoption in tissue diagnostics: A comprehensive review.

Hyperspectral imaging (HSI) has become an evident transformative apparatus in medical diagnostics. The review aims to appraise the present advancement and challenges in HSI for medical applications. It features a variety of medical applications namely diagnosing diabetic retinopathy, neurodegenerative diseases like Parkinson's and Alzheimer's, which illustrates its effectiveness in early diagnosis, early caries detection in periodontal disease, and dermatology by detecting skin cancer. Regardless of these advances, the challenges exist within every aspect that limits its broader clinical adoption. It has various constraints including difficulties with technology related to the complexity of the HSI system and needing specialist training, which may act as a drawback to its clinical settings. This article pertains to potential challenges expressed in medical applications and probable solutions to overcome these constraints. Successful companies that perform advanced solutions with HSI in terms of medical applications are being emphasized in this study to signal the high level of interest in medical diagnosis for systems to incorporate machine learning ML and artificial intelligence AI to foster precision diagnosis and standardized clinical workflow. This advancement signifies progressive possibilities of HSI in real-time clinical assessments. In conclusion despite HSI has been presented as a significant advanced medical imaging tool, addressing its limitations and probable solutions is for broader clinical adoption.

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来源期刊
APL Bioengineering
APL Bioengineering ENGINEERING, BIOMEDICAL-
CiteScore
9.30
自引率
6.70%
发文量
39
审稿时长
19 weeks
期刊介绍: APL Bioengineering is devoted to research at the intersection of biology, physics, and engineering. The journal publishes high-impact manuscripts specific to the understanding and advancement of physics and engineering of biological systems. APL Bioengineering is the new home for the bioengineering and biomedical research communities. APL Bioengineering publishes original research articles, reviews, and perspectives. Topical coverage includes: -Biofabrication and Bioprinting -Biomedical Materials, Sensors, and Imaging -Engineered Living Systems -Cell and Tissue Engineering -Regenerative Medicine -Molecular, Cell, and Tissue Biomechanics -Systems Biology and Computational Biology
期刊最新文献
Substrate stiffness modulates collective colony expansion of the social bacterium Myxococcus xanthus. Stem cell mechanoadaptation. I. Effect of microtubule stabilization and volume changing stresses on cytoskeletal remodeling. Stem cell mechanoadaptation. II. Microtubule stabilization and substrate compliance effects on cytoskeletal remodeling. Unpleasant odors compared to pleasant ones cause higher cortical activations detectable by fNIRS and observable mostly in females. Organs-on-chips: Advanced engineered living systems.
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