Eosinophils were Significantly Elevated in the Chronic Subdural Hematoma Fluids: Two Case Reports.

Background: Chronic subdural hematoma (CSDH) is a type of spontaneous or post-traumatic intracranial hemorrhage located between the dura mater and arachnoid membrane. It is a neurosurgical disease that often occurs in the elderly. Burr-hole drainage is the main treatment method, and smear microscopic examination of the drainage fluid is a common laboratory method.

Methods: A cranial magnetic resonance imaging (MRI) was performed, then blood and drainage fluid from patients with CSDH was collected and sent to the laboratory for routine laboratory tests.

Results: Both patients' cranial MRI indicated CSDH, while no significant abnormalities were found in blood-related tests. Microscopic examination of postoperative drainage fluid revealed a significantly increased proportion of eosinophils.

Conclusions: It is found that the mechanism of eosinophil infiltration in CSDH and its significance for patients are still unclear by combining the cases and relevant literatures. Further research is needed to study the distribution and changes of eosinophils and related chemokines in the peripheral blood and postoperative drainage fluid from CSDH patients, which is of great significance for the treatment and recurrence prediction of CSDH patients.