Erin Delker, Rebecca J Baer, Christina D Chambers, Gretchen Bandoli
{"title":"在加州医疗补助资助出生的三个行政数据来源中确定妊娠期慢性高血压。","authors":"Erin Delker, Rebecca J Baer, Christina D Chambers, Gretchen Bandoli","doi":"10.1002/pds.70059","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose: </strong>Administrative data sources are used to describe the epidemiology of chronic hypertension in pregnancy and its consequences. Differences in identification across sources may affect research estimates. We compared identification of chronic hypertension in birth certificate records, hospital discharge records, and Medi-Cal claims in the same individuals.</p><p><strong>Methods: </strong>We used data from 820 140 2016-2020 California Medi-Cal covered births. We identified chronic hypertension on birth certificates using the prepregnancy hypertension check box and in hospital discharge records and Medi-Cal claims using ICD codes. We compared the prevalence of chronic hypertension and identified predictors of agreement. We also compared absolute and relative estimates of racial/ethnic disparities in chronic hypertension and associations with neonatal outcomes.</p><p><strong>Results: </strong>The prevalence of chronic hypertension was 0.7% in birth records, 2.1% in hospital discharge records, and 3.9% in Medi-Cal claims. There was low to fair agreement between birth certificate records and hospitalization records (kappa = 0.36) and Medi-Cal claims (kappa = 0.25). Characteristics associated with the worst agreement were eligibility for Women Infant and Children benefits, US-born, and normal body mass index. Estimates of the relative risk for racial/ethnic disparities and associations with preterm birth and SGA age at delivery were similar across sources. Estimates of risk differences were larger in hospitalization and Medi-Cal claims data.</p><p><strong>Conclusions: </strong>Reliance on birth certificate data may contribute to underestimated prevalence estimates and biased causal estimates. Epidemiologic research and public health surveillance of chronic hypertension and its consequences should incorporate data from multiple data sources to improve validity of estimates.</p>","PeriodicalId":19782,"journal":{"name":"Pharmacoepidemiology and Drug Safety","volume":"33 12","pages":"e70059"},"PeriodicalIF":2.4000,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11634560/pdf/","citationCount":"0","resultStr":"{\"title\":\"Identification of Chronic Hypertension in Pregnancy in Three Administrative Data Sources Among Medicaid-Funded Births in California.\",\"authors\":\"Erin Delker, Rebecca J Baer, Christina D Chambers, Gretchen Bandoli\",\"doi\":\"10.1002/pds.70059\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Purpose: </strong>Administrative data sources are used to describe the epidemiology of chronic hypertension in pregnancy and its consequences. Differences in identification across sources may affect research estimates. We compared identification of chronic hypertension in birth certificate records, hospital discharge records, and Medi-Cal claims in the same individuals.</p><p><strong>Methods: </strong>We used data from 820 140 2016-2020 California Medi-Cal covered births. We identified chronic hypertension on birth certificates using the prepregnancy hypertension check box and in hospital discharge records and Medi-Cal claims using ICD codes. We compared the prevalence of chronic hypertension and identified predictors of agreement. We also compared absolute and relative estimates of racial/ethnic disparities in chronic hypertension and associations with neonatal outcomes.</p><p><strong>Results: </strong>The prevalence of chronic hypertension was 0.7% in birth records, 2.1% in hospital discharge records, and 3.9% in Medi-Cal claims. There was low to fair agreement between birth certificate records and hospitalization records (kappa = 0.36) and Medi-Cal claims (kappa = 0.25). Characteristics associated with the worst agreement were eligibility for Women Infant and Children benefits, US-born, and normal body mass index. Estimates of the relative risk for racial/ethnic disparities and associations with preterm birth and SGA age at delivery were similar across sources. Estimates of risk differences were larger in hospitalization and Medi-Cal claims data.</p><p><strong>Conclusions: </strong>Reliance on birth certificate data may contribute to underestimated prevalence estimates and biased causal estimates. Epidemiologic research and public health surveillance of chronic hypertension and its consequences should incorporate data from multiple data sources to improve validity of estimates.</p>\",\"PeriodicalId\":19782,\"journal\":{\"name\":\"Pharmacoepidemiology and Drug Safety\",\"volume\":\"33 12\",\"pages\":\"e70059\"},\"PeriodicalIF\":2.4000,\"publicationDate\":\"2024-12-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11634560/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Pharmacoepidemiology and Drug Safety\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1002/pds.70059\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"PHARMACOLOGY & PHARMACY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Pharmacoepidemiology and Drug Safety","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1002/pds.70059","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"PHARMACOLOGY & PHARMACY","Score":null,"Total":0}
Identification of Chronic Hypertension in Pregnancy in Three Administrative Data Sources Among Medicaid-Funded Births in California.
Purpose: Administrative data sources are used to describe the epidemiology of chronic hypertension in pregnancy and its consequences. Differences in identification across sources may affect research estimates. We compared identification of chronic hypertension in birth certificate records, hospital discharge records, and Medi-Cal claims in the same individuals.
Methods: We used data from 820 140 2016-2020 California Medi-Cal covered births. We identified chronic hypertension on birth certificates using the prepregnancy hypertension check box and in hospital discharge records and Medi-Cal claims using ICD codes. We compared the prevalence of chronic hypertension and identified predictors of agreement. We also compared absolute and relative estimates of racial/ethnic disparities in chronic hypertension and associations with neonatal outcomes.
Results: The prevalence of chronic hypertension was 0.7% in birth records, 2.1% in hospital discharge records, and 3.9% in Medi-Cal claims. There was low to fair agreement between birth certificate records and hospitalization records (kappa = 0.36) and Medi-Cal claims (kappa = 0.25). Characteristics associated with the worst agreement were eligibility for Women Infant and Children benefits, US-born, and normal body mass index. Estimates of the relative risk for racial/ethnic disparities and associations with preterm birth and SGA age at delivery were similar across sources. Estimates of risk differences were larger in hospitalization and Medi-Cal claims data.
Conclusions: Reliance on birth certificate data may contribute to underestimated prevalence estimates and biased causal estimates. Epidemiologic research and public health surveillance of chronic hypertension and its consequences should incorporate data from multiple data sources to improve validity of estimates.
期刊介绍:
The aim of Pharmacoepidemiology and Drug Safety is to provide an international forum for the communication and evaluation of data, methods and opinion in the discipline of pharmacoepidemiology. The Journal publishes peer-reviewed reports of original research, invited reviews and a variety of guest editorials and commentaries embracing scientific, medical, statistical, legal and economic aspects of pharmacoepidemiology and post-marketing surveillance of drug safety. Appropriate material in these categories may also be considered for publication as a Brief Report.
Particular areas of interest include:
design, analysis, results, and interpretation of studies looking at the benefit or safety of specific pharmaceuticals, biologics, or medical devices, including studies in pharmacovigilance, postmarketing surveillance, pharmacoeconomics, patient safety, molecular pharmacoepidemiology, or any other study within the broad field of pharmacoepidemiology;
comparative effectiveness research relating to pharmaceuticals, biologics, and medical devices. Comparative effectiveness research is the generation and synthesis of evidence that compares the benefits and harms of alternative methods to prevent, diagnose, treat, and monitor a clinical condition, as these methods are truly used in the real world;
methodologic contributions of relevance to pharmacoepidemiology, whether original contributions, reviews of existing methods, or tutorials for how to apply the methods of pharmacoepidemiology;
assessments of harm versus benefit in drug therapy;
patterns of drug utilization;
relationships between pharmacoepidemiology and the formulation and interpretation of regulatory guidelines;
evaluations of risk management plans and programmes relating to pharmaceuticals, biologics and medical devices.