定制关节垫片(CUMARS)一期和半期全髋关节置换术治疗双侧破坏性髋关节感染性关节炎1例报告。

Hui-Shan Angela Lim, Kuei Siong Andy Yeo, Raghavan Raghuraman, Kam King Charles Kon, Ing How Moo
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摘要

摘要:脓毒性关节炎的及时诊断和治疗对于早期根除感染、保护关节和预防影响生活质量的后果至关重要。全髋关节置换术已被引入到严重破坏性败血性关节炎的治疗中,目的是在保持髋关节功能的同时根除感染。很少有案例研究使用含抗生素丙烯酸水泥关节间隔器的假体进行两期置换全髋关节置换术治疗先天性髋关节脓毒性关节炎,总体效果良好。然而,一小部分患者选择性地选择不进行第二阶段的置换关节置换术。因此,1.5期全髋关节置换术被认为是一个可行的选择;然而,它只在假体周围感染管理中建立,而不是在原发性髋关节脓毒性关节炎中建立。定制的关节隔离器被认为是一种理想的选择,因为它没有限制,更容易获得,并且被设计成一种功能单一的隔离器,可以保持永久性,但如果需要,不排除进行第二阶段交换手术的可能性。总的来说,这导致考虑使用定制的关节间隔器进行1.5期全髋关节置换术来治疗慢性破坏性髋关节脓毒性关节炎。病例报告:我们报告了一位67岁的患者,在没有辅助的情况下,从完全独立的功能下降到坐在椅子上超过8个月。检查显示炎症标志物升高和双侧破坏性髋关节脓毒性关节炎。他接受了双侧1.5期全髋关节置换术,使用了装有抗生素的定制关节垫片。手术后一年,他仍然没有感染,康复进展良好,可以用步行架独立行走。结论:脓毒性关节炎的治疗在很大程度上取决于感染时间、活动水平和关节破坏程度。在严重破坏的髋关节脓毒性关节炎中,使用含抗生素的定制关节间隔器进行1.5期全髋关节置换术是一种可行的选择,具有有效根除感染,良好的功能结果,成本效益,减少身体和心理负担,避免第二次手术的好处,同时不排除在需要时轻松进行第二期置换关节置换术的可能性。
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One and a Half-stage Total Hip Arthroplasty with Custom-Made Articulating Spacers (CUMARS) for Management of Bilateral Destructive Hip Septic Arthritis - A Case Report.

Introduction: Prompt diagnosis and management of septic arthritis are pivotal for early infection eradication, joint preservation, and prevention of quality-of-life impact consequences. Total hip arthroplasty has been introduced for the management of severe destructive septic arthritis with the aims to eradicate infection while preserving hip function. Few case studies have been done on two-stage exchange total hip arthroplasty for treatment of native hip septic arthritis using prosthesis with antibiotic-loaded acrylic cement articulating spacer with generally good outcomes. However, a small percentage of patients electively chose not to proceed with the second-stage exchange arthroplasty. Therefore, 1.5-stage total hip arthroplasty was considered a viable option; however, it has only been established in periprosthetic infection management, but not in native hip septic arthritis. Custom-made articulating spacers are considered an ideal option as has no constraints, are more readily available, and were designed to be a functional single-stage spacer that can remain permanent yet not preclude the possibility of a second-stage exchange surgery if required. Overall, this led to the consideration of 1.5-stage total hip arthroplasty using custom-made articulating spacers for the management of chronic destructive hip septic arthritis.

Case report: We report a 67-year-old patient with functional decline from fully independent without aids to chairbound over 8 months. Work-up revealed raised inflammatory markers and bilateral destructive hip septic arthritis. He underwent bilateral 1.5-stage total hip arthroplasty with antibiotic-loaded custom-made articulating spacers. One-year post-operation, he remains infection-free and is progressing well with rehabilitation - ambulating independently with walking frame.

Conclusion: Management of septic arthritis varies largely depending on infection duration, activity level, and extent of joint destruction. In significantly destructed hip septic arthritis, 1.5-stage total hip arthroplasty using antibiotic-loaded custom-made articulating spacer is a viable option with the benefits of effective infection eradication, good functional outcomes, cost-effectiveness, reduced physical and psychological burden in avoiding a second operation, all whilst not precluding the possibility of a second-stage exchange arthroplasty if required with ease.

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