用于个性化医疗的电子健康记录分析:预测与营养不良相关的健康结果和继发性神经精神健康问题。

Pinar Gurkas, Gunnur Karakurt
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引用次数: 0

摘要

营养不良会给认知、行为和身体健康带来风险。本研究的目的是利用电子健康记录(EHR)数据调查与营养不良相关的普遍健康问题。使用IBM Watson Health, Explorys平台访问EHR数据。两个队列由两个查询创建;有营养不良史的患者(n=5180)和无营养不良诊断史的患者(n= 413890)。采用对数比值比和χ2统计分析两组间差异有统计学意义。我们发现有35个术语在诊断为营养不良的队列中更为常见。这些术语被分类为发育异常、传染因子、呼吸系统问题、消化系统问题、怀孕/产前问题、精神、行为或神经发育障碍、耳或乳突疾病、视觉系统疾病和染色体异常。儿童营养不良的管理是一个复杂的问题,可以通过多因素方法来解决。基于在我们的研究中确定的常见术语中出现的关键主题,感染预防,针对消化系统健康问题的适当营养解决方案的教育,解决神经发育需求的支持性服务以及高质量的产前保健将构成有益的预防工作。提高我们对营养不良的认识对于开发新的预防和治疗干预措施是必要的。
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Electronic Health Record Analysis for Personalized Medicine: Predicting Malnutrition-Related Health Outcomes and Secondary Neuropsychiatric Health Concerns.

Malnutrition poses risks regarding cognitive, behavioral, and physical well-being. The aim of this study was to investigate the prevalent health issues associated with malnutrition by utilizing electronic health records (EHR) data. The IBM Watson Health, Explorys platform was used to access the EHR data. Two cohorts were created by two queries; patients with a history of malnutrition (n=5180) and patients without a history of malnutrition diagnosis (n= 413890). The log odds ratio and χ2 statistic were used to identify the statistically significant differences between these two cohorts. We found that there were 35 terms that were more common among the cohort with the malnutrition diagnosis. These terms were categorized under developmental anomalies, infectious agents, respiratory system issues, digestive system issues, pregnancy/prenatal problems, mental, behavioral, or neurodevelopmental disorders, diseases of the ear or mastoid process, diseases of the visual system, and chromosomal anomalies. The management of malnutrition in children is a complex problem that can be addressed with a multifactorial approach. Based on the key themes emerging from among the commonly prevalent terms identified in our study, infection prevention, education in appropriate nutritional solutions for digestive health issues, supportive services to address neurodevelopmental needs, and quality prenatal healthcare would constitute beneficial prevention efforts. Improving our understanding of malnutrition is necessary to develop new interventions for prevention and treatment.

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