Bardiya Zangbar, Nicole Lin, Aryan Rafieezadeh, Jordan Kirsch, Ilya Shnaydman, Lars Eckenberg, Gabriel Froula, Joshua Klein, Matthew Bronstein, Kartik Prabhakaran
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Outcomes were compared between patients with obesity (BMI≥30 kg∖m<sup>2</sup>) and overweight (25 kg∖m<sup>2</sup>≤BMI<30 kg∖m<sup>2</sup>) and normal weight (19 kg∖m<sup>2</sup>≤BMI<25 kg∖m<sup>2</sup>) patients.</div></div><div><h3>Results</h3><div>A total number of 30,356 (26.8 %) patients were obese. All clotting complications (stroke/CVA, MI, DVT and PE) were significantly more frequent among obese patients (p < 0.001for all). Multivariate logistic regression showed that obese patients had significantly increased odds of stroke/CVA (OR = 1.207), MI (OR = 1.301), DVT (OR = 1.311) and PE (OR = 1.241) (p < 0.001 for all).</div></div><div><h3>Conclusion</h3><div>Obese geriatric patients who sustain severe traumatic injuries are at increased risk of thromboembolic complications compared to non-obese patients.</div></div><div><h3>Level of evidence</h3><div>Level III retrospective study.</div></div>","PeriodicalId":7771,"journal":{"name":"American journal of surgery","volume":"240 ","pages":"Article 116139"},"PeriodicalIF":2.7000,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Obesity portends an increased risk of thromboembolic events in severely injured geriatric trauma, a retrospective study\",\"authors\":\"Bardiya Zangbar, Nicole Lin, Aryan Rafieezadeh, Jordan Kirsch, Ilya Shnaydman, Lars Eckenberg, Gabriel Froula, Joshua Klein, Matthew Bronstein, Kartik Prabhakaran\",\"doi\":\"10.1016/j.amjsurg.2024.116139\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Background</h3><div>Obesity is a known risk factor for thromboembolic complications in trauma patients. 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引用次数: 0
摘要
背景：肥胖是创伤患者血栓栓塞并发症的已知危险因素。我们研究的目的是评估肥胖老年患者血栓性并发症的患病率。方法：对TQIP（2017-2019）进行回顾性分析。共纳入119,906例≥65岁的严重创伤患者。主要结局是血栓性并发症，包括脑卒中/脑血管意外（CVA）、心肌梗死（MI）、深静脉血栓形成（DVT）和肺栓塞（PE）。比较肥胖（BMI≥30 kg / m2）、超重（25 kg / m2≤BMI2）和正常体重（19 kg / m2≤BMI2）患者的结局。结果：30356例（26.8%）患者为肥胖。所有凝血并发症（卒中/CVA、心肌梗死、DVT和PE）在肥胖患者中明显更频繁(p结论：与非肥胖患者相比，遭受严重创伤的肥胖老年患者发生血栓栓塞并发症的风险更高。证据等级：III级回顾性研究。
Obesity portends an increased risk of thromboembolic events in severely injured geriatric trauma, a retrospective study
Background
Obesity is a known risk factor for thromboembolic complications in trauma patients. The aim of our study is to evaluate the prevalence of thrombotic complications in obese geriatric patients.
Methods
We performed a retrospective analysis of TQIP (2017–2019). A total of 119,906 patients≥65 years who sustained severe trauma were included. Primary outcomes were thrombotic complications including stroke/cerebrovascular accidents (CVA), myocardial infarction (MI), deep vein thrombosis (DVT) and pulmonary embolism (PE). Outcomes were compared between patients with obesity (BMI≥30 kg∖m2) and overweight (25 kg∖m2≤BMI<30 kg∖m2) and normal weight (19 kg∖m2≤BMI<25 kg∖m2) patients.
Results
A total number of 30,356 (26.8 %) patients were obese. All clotting complications (stroke/CVA, MI, DVT and PE) were significantly more frequent among obese patients (p < 0.001for all). Multivariate logistic regression showed that obese patients had significantly increased odds of stroke/CVA (OR = 1.207), MI (OR = 1.301), DVT (OR = 1.311) and PE (OR = 1.241) (p < 0.001 for all).
Conclusion
Obese geriatric patients who sustain severe traumatic injuries are at increased risk of thromboembolic complications compared to non-obese patients.
期刊介绍：
The American Journal of Surgery® is a peer-reviewed journal designed for the general surgeon who performs abdominal, cancer, vascular, head and neck, breast, colorectal, and other forms of surgery. AJS is the official journal of 7 major surgical societies* and publishes their official papers as well as independently submitted clinical studies, editorials, reviews, brief reports, correspondence and book reviews.
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