复合去充血疗法可提高下肢淋巴水肿患者的步速

IF 1.6 4区 医学 Q3 MEDICINE, RESEARCH & EXPERIMENTAL Lymphatic research and biology Pub Date : 2025-02-01 Epub Date: 2024-12-17 DOI:10.1089/lrb.2024.0021
Evrim Gökçe, Neslişah Gün, Ülkü Düzlü Öztürk, Meltem Dalyan
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引用次数: 0

摘要

背景:继发性淋巴水肿是后天形成的,由正常发育的淋巴系统受阻或损伤引起。在癌症治疗后继发性下肢淋巴水肿(LLL)患者中,丧失活动能力是一个常见问题。在这项研究中,我们探讨了复合去充血疗法(CDT)对下肢淋巴水肿患者运动功能和活动能力的影响。方法和结果:我们对 24 名 LLL 2 期患者(56.04 ± 14.23 岁)进行了准实验研究。参与者接受了 15 次 CDT 治疗。运动功能通过足拍击测试(FTT)进行评估。在单任务(ST)和双任务(DT)条件下测量步速,并计算 DT 成本。所有评估均在干预前后进行。采用配对 t 检验和 Wilcoxon 符号秩检验分析 CDT 对 FTT、步速和 DT 成本的影响。CDT 后,ST 和 DT 步速(p = 0.002,p < 0.001)和 DT 成本(p = 0.001)均有所下降,而双侧 FTT 评分没有变化。结论CDT 改善了 LLL 的活动能力和双重任务能力,从而提高了日常生活的独立性。今后需要进行前瞻性对照研究,以证实我们的结果。
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Complex Decongestive Therapy Improves Gait Speed in Patients with Lower Limb Lymphedema.

Background: Secondary lymphedema is acquired and caused by obstruction or injury to a normally developed lymphatic system. Loss of mobility is a common problem in patients with secondary lower limb lymphedema (LLL) following cancer treatment. In this study, we examined the effect of complex decongestive therapy (CDT) on motor function and mobility in patients with LLL. Methods and Results: A quasi-experimental study was performed with 24 participants with stage 2 LLL (56.04 ± 14.23 years). Participants received 15 sessions of CDT. Motor function was assessed with a foot tapping test (FTT). Gait speed was measured in single-task (ST) and dual-task (DT) conditions, and DT cost was calculated. All assessments were performed before and after the intervention. The paired t-test and Wilcoxon signed-rank test were used to analyze the effect of CDT on FTT, gait speed, and DT cost. ST and DT gait speed (p = 0.002, p < 0.001) and DT cost (p = 0.001) decreased following the CDT, whereas bilateral FTT scores did not change. Conclusion: CDT improves mobility and dual-tasking in LLL, thereby promoting independence in daily life. Future prospective controlled studies are required to corroborate our results.

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来源期刊
Lymphatic research and biology
Lymphatic research and biology Medicine-Cardiology and Cardiovascular Medicine
CiteScore
3.10
自引率
7.10%
发文量
85
审稿时长
>12 weeks
期刊介绍: Lymphatic Research and Biology delivers the most current peer-reviewed advances and developments in lymphatic biology and pathology from the world’s leading biomedical investigators. The Journal provides original research from a broad range of investigative disciplines, including genetics, biochemistry and biophysics, cellular and molecular biology, physiology and pharmacology, anatomy, developmental biology, and pathology. Lymphatic Research and Biology coverage includes: -Vasculogenesis and angiogenesis -Genetics of lymphatic disorders -Human lymphatic disease, including lymphatic insufficiency and associated vascular anomalies -Physiology of intestinal fluid and protein balance -Immunosurveillance and immune cell trafficking -Tumor biology and metastasis -Pharmacology -Lymphatic imaging -Endothelial and smooth muscle cell biology -Inflammation, infection, and autoimmune disease
期刊最新文献
Assessment Tools to Quantify the Physical Aspects of Lipedema: A Systematic Review. Efficacy of Therapeutic Ultrasound Added to Complex Decongestive Therapy in Breast Cancer-Related Lymphedema. Evaluation of Elastographic Parameters in Patients with Breast Cancer-Related Lymphedema and Examination of Their Relationship with Clinical Data. A New Secondary Chronic Lymphedema Rat Model Improved by High-Fat Diet. Characteristic Computed Tomography Findings in Female Patients with Secondary Genital Lymphedema.
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