心肺运动能力对经皮冠状动脉介入治疗冠心病患者临床预后的影响

IF 2.1 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL International Journal of General Medicine Pub Date : 2024-12-14 eCollection Date: 2024-01-01 DOI:10.2147/IJGM.S490833
Wen Zhang, Jinguo Xu
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引用次数: 0

摘要

目的:分析冠心病患者经皮冠状动脉介入治疗(PCI)后心肺功能与预后的关系。方法:2018年1月至2020年4月,153例冠心病患者接受了PCI治疗。经仔细评估,于PCI术后5 ~ 7天进行心肺运动试验(CPX)。出院后每3个月进行一次门诊检查或电话随访,随访3年。随访的临床结果包括心源性死亡、再住院、心力衰竭、心房颤动、脑卒中和短暂性脑缺血发作。将单个临床事件定义为预后不良,并根据预后分为预后良好组和预后不良组。通过比较心肺适能(CRF)变量与临床参数,确定可能影响患者预后的变量。结果:预后不良组CRF显著降低,峰值VO2、VO2/kg AT、PETCO2、OUES较预后良好组降低,差异均有统计学意义。预后差组心率储备(HRR)较预后好组增高,差异有统计学意义。其中VO2峰值和急性心肌梗死是预后不良的独立危险因素。结论:VO2峰值是影响冠心病PCI术后心血管疾病预后的独立危险因素。
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The Effect of Cardiopulmonary Exercise Ability to Clinical Outcomes of Patients with Coronary Artery Disease Undergoing Percutaneous Coronary Intervention.

Objective: To analyze the relationship between the cardiopulmonary function and prognosis of patients with coronary heart disease after percutaneous coronary intervention (PCI).

Methods: A total of 153 patients with coronary heart disease who underwent PCI from January 2018 to April 2020 were enrolled in this study. Through careful assessment, cardiopulmonary exercise test (CPX) was performed 5 to 7 days after PCI. Patients were followed up every 3 months by outpatient examination or telephone visiting for 3 years after discharge. Clinical outcomes were followed up, including cardiac death, rehospitalization, heart failure, atrial fibrillation, stroke and transient ischemic attack. A single clinical event was defined as a poor prognosis and divided into a good prognosis group and a poor prognosis group according to the prognosis. By comparing the cardiorespiratory fitness (CRF) variables and clinical parameters, the variables that may affect the prognosis of patients were determined.

Results: CRF decreased significantly in the poor prognosis group, and peak VO2, VO2/kg AT, PETCO2 and OUES decreased compared with the good prognosis group, and the differences were statistically significant. Heart rate reserve (HRR) increased in the poor prognosis group compared with the good prognosis group, and the difference was statistically significant. Among them, peak VO2 and acute myocardial infarction were independent risk factors for poor prognosis.

Conclusion: Peak VO2 is an independent risk factor for the prognosis of cardiovascular disease after PCI for coronary heart disease.

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来源期刊
International Journal of General Medicine
International Journal of General Medicine Medicine-General Medicine
自引率
0.00%
发文量
1113
审稿时长
16 weeks
期刊介绍: The International Journal of General Medicine is an international, peer-reviewed, open access journal that focuses on general and internal medicine, pathogenesis, epidemiology, diagnosis, monitoring and treatment protocols. The journal is characterized by the rapid reporting of reviews, original research and clinical studies across all disease areas. A key focus of the journal is the elucidation of disease processes and management protocols resulting in improved outcomes for the patient. Patient perspectives such as satisfaction, quality of life, health literacy and communication and their role in developing new healthcare programs and optimizing clinical outcomes are major areas of interest for the journal. As of 1st April 2019, the International Journal of General Medicine will no longer consider meta-analyses for publication.
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