Zhiping Liu, Jie Pang, Lijie Che, Chunfang Gan, Jianguo Cui, Yanmin Huang
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GaCl3-Catalyzed [3 + 2]-Cycloaddition/Esterification Cascade of Donor–Acceptor Cyclopropanes With Salicylaldehydes for the Synthesis of Tetrahydro-4
H-Furo[3,2-c]Chromen-4-Ones
A GaCl3-catalyzed [3 + 2]-cycloaddition/intramolecular esterification cascade of donor–acceptor cyclopropane-1,1-diesters with salicylaldehydes has been reported. A wide range of tetrahydro-4H-furo[3,2-c]chromen-4-ones have been efficiently delivered in moderate to good yields. Mechanistic studies suggest that the reaction involves the [3 + 2]-cycloaddition followed by intramolecular esterification to access 4H-furo[3,2-c]chromenones.
期刊介绍：
The Journal of Heterocyclic Chemistry is interested in publishing research on all aspects of heterocyclic chemistry, especially development and application of efficient synthetic methodologies and strategies for the synthesis of various heterocyclic compounds. In addition, Journal of Heterocyclic Chemistry promotes research in other areas that contribute to heterocyclic synthesis/application, such as synthesis design, reaction techniques, flow chemistry and continuous processing, multiphase catalysis, green chemistry, catalyst immobilization and recycling.
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