手术和麻醉平台试验之间的全球合作。

IF 9.1 1区医学 Q1 ANESTHESIOLOGY British journal of anaesthesia Pub Date : 2024-12-18 DOI:10.1016/j.bja.2024.09.021

James Glasbey, Steve A Webb, Trisha Peel, Thomas D Pinkney, Paul S Myles

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引用次数: 0

摘要

大型随机试验是循证医学的基础，但完成此类试验所需的资源极大地限制了在合理时间内可以解决的重要临床问题的数量。适应性平台试验可以更快地识别有效、无效或有害的治疗方法。这些试验已被证明能够在2019冠状病毒病大流行期间快速提供证据，目前已被应用于外科和麻醉领域，为外科医生、麻醉师和其他围手术期医生提供了许多开展平台试验并开展合作的机会。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Global collaboration between platform trials in surgery and anaesthesia.

Large, randomised trials are the bedrock of evidence-based medicine, but the resources required to complete such trials greatly limit the number of important clinical questions that can be addressed within a reasonable period of time. Adaptive platform trials can identify effective, ineffective, or harmful treatments faster. These trials have been shown to deliver rapid evidence through the COVID-19 pandemic and are now being adopted across surgery and anaesthesia, with many opportunities for surgeons, anaesthetists, and other perioperative physicians to conduct and collaborate in platform trials.

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来源期刊

British journal of anaesthesia 医学-麻醉学

CiteScore

13.50

自引率

7.10%

发文量

488

审稿时长

27 days

期刊介绍： The British Journal of Anaesthesia (BJA) is a prestigious publication that covers a wide range of topics in anaesthesia, critical care medicine, pain medicine, and perioperative medicine. It aims to disseminate high-impact original research, spanning fundamental, translational, and clinical sciences, as well as clinical practice, technology, education, and training. Additionally, the journal features review articles, notable case reports, correspondence, and special articles that appeal to a broader audience. The BJA is proudly associated with The Royal College of Anaesthetists, The College of Anaesthesiologists of Ireland, and The Hong Kong College of Anaesthesiologists. This partnership provides members of these esteemed institutions with access to not only the BJA but also its sister publication, BJA Education. It is essential to note that both journals maintain their editorial independence. Overall, the BJA offers a diverse and comprehensive platform for anaesthetists, critical care physicians, pain specialists, and perioperative medicine practitioners to contribute and stay updated with the latest advancements in their respective fields.