【经胃肠道出血发现睾丸绒毛膜癌肠转移一例】。

Rei Ueno, Shunsuke Shinmei, Hayato Yoshioka, Tomoyo Murasawa, Yusuke Imura, Kousuke Sadahide, Yoshimasa Kurimura, Mitsuru Kajiwara
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引用次数: 0

摘要

一名26岁男性以咯血和右阴囊肿胀主诉到医院就诊。CT显示右侧睾丸肿胀,多发肺转移,小肠壁增厚。患者β-人绒毛膜促性腺激素、甲胎蛋白、乳酸脱氢酶、血红蛋白水平分别为103.3 ng/ml、20.8 ng/ml、300 U/l、11.3 g/dl。在被诊断出睾丸肿瘤和多处肺转移后,他接受了高睾丸切除术。组织病理检查显示为混合性生殖细胞瘤(60%绒毛膜癌,20%精原细胞瘤,10%胚胎癌,10%成熟畸胎瘤,1%卵黄囊瘤)。由于患者表现为活动性胃肠出血,需要频繁输血,因此行胃肠内镜检查以调查其原因。上下消化道内窥镜检查均未发现出血,患者转至我院进一步检查治疗。小肠内窥镜检查显示空肠出血性肿块。由于内窥镜止血困难,我们切除了部分小肠。切除病灶的病理表现与睾丸肿瘤小肠转移一致。经4个周期的BEP和4个周期的TIP化疗后,肿瘤标志物转为阴性。术后1年未见肿瘤残留或复发。
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[A Case of Intestinal Metastasis of Testicular Choriocarcinoma Revealed Through Gastrointestinal Bleeding].

A 26-year-old male presented to a hospital with complaints of hemoptysis and right scrotal swelling. Computed tomography (CT) revealed right testicular swelling, multiple lung metastases, and small intestinal wall thickening. The patient's β-human chorionic gonadotropin, alpha-fetoprotein, lactate dehydrogenase, and hemoglobin levels were 103.3 ng/ml, 20.8 ng/ml, 300 U/l, and 11.3 g/dl, respectively. He underwent high orchidectomy after being diagnosed with a testicular tumor and multiple lung metastases. Histopathological examination revealed a mixed germ cell tumor (60% choriocarcinoma, 20% seminoma, 10% embryonal carcinoma, 10% mature teratoma, and 1% yolk sac tumor). As the patient exhibited active gastrointestinal hemorrhage requiring frequent blood transfusions, gastrointestinal endoscopy was performed to investigate its cause. When upper and lower gastrointestinal endoscopies revealed no bleeding, the patient was referred to our hospital for further examination and treatment. A small bowel endoscopy revealed a hemorrhagic jejunal mass. Because endoscopic hemostasis was challenging, we partially resected the small intestine. Pathological findings in the resected lesion were consistent with small intestinal metastasis of the testicular tumor. The tumor markers turned negative after four cycles of BEP and four cycles of TIP chemotherapy. He then underwent resection of the remaining lung tumor, and no residual tumor or recurrence was detected one year later.

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来源期刊
Acta Urologica Japonica
Acta Urologica Japonica Medicine-Medicine (all)
CiteScore
0.20
自引率
0.00%
发文量
74
期刊最新文献
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