肠道菌群对肾移植后糖尿病治疗的影响。

IF 2.2 4区 医学 Q2 UROLOGY & NEPHROLOGY BMC Nephrology Pub Date : 2024-12-23 DOI:10.1186/s12882-024-03899-y
Luo-Bei Chen, Qian Chen, Sheng Chao, Zhi-Hui Yuan, Lei Jia, Yu-Lin Niu
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引用次数: 0

摘要

移植后糖尿病(PTDM)是肾移植术后常见的并发症,近年来发病率逐渐上升,对公共卫生构成重大挑战。治疗PTDM是复杂的,因为研究表明它涉及到跨多个器官的微生物菌群的变化。最近的研究强调了肠道菌群代谢在肾移植后患者糖尿病发展中的关键作用。本文综述了PTDM患者肠道菌群的变化,并探讨了肠道菌群对PTDM的影响。这些发现可能为针对肠道菌群代谢物预防和治疗PTDM提供新的视角。
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Influence of gut flora on diabetes management after kidney transplantation.

Post-transplant diabetes mellitus (PTDM) is a common complication following renal transplantation, and its incidence has been gradually increasing in recent years, posing a significant public health challenge. Managing PTDM is complex, as studies suggest that it involves changes in the microbial flora across multiple organs. Recent research highlights the critical role of gut flora metabolism in the development of diabetes among post-renal transplant patients. This paper reviews the alterations in gut flora observed in PTDM patients and explores how gut flora influences PTDM. These findings may offer new perspectives on targeting gut flora metabolites for the prevention and treatment of PTDM.

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来源期刊
BMC Nephrology
BMC Nephrology UROLOGY & NEPHROLOGY-
CiteScore
4.30
自引率
0.00%
发文量
375
审稿时长
3-8 weeks
期刊介绍: BMC Nephrology is an open access journal publishing original peer-reviewed research articles in all aspects of the prevention, diagnosis and management of kidney and associated disorders, as well as related molecular genetics, pathophysiology, and epidemiology.
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