帕金森氏病眼部疾病的研究:综述与展望

IF 3 2区 医学 Q1 OPHTHALMOLOGY Experimental eye research Pub Date : 2024-12-24 DOI:10.1016/j.exer.2024.110225
Minal Thacker, Ka Ying Wong, Liping Zhou, Juewen Liu, Man-Sau Wong
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引用次数: 0

摘要

帕金森病(PD)是一种以运动症状为主的多方面神经退行性疾病。然而,最近的研究通过揭示PD对包括眼部表现在内的非运动功能的影响,拓宽了我们对PD的理解。本文探讨了PD与眼部健康之间的复杂关系,揭示了干眼病、白内障、青光眼、年龄相关性黄斑变性和糖尿病视网膜病变等常见眼部疾病的发病机制。它还强调了将眼部表现视为PD的潜在早期标志的重要性,以及它们对患者日常活动的影响,需要及时识别和干预,以预防并发症并提高整体生活质量。此外,未来的研究应优先揭示PD与其他常见眼部疾病(如近视)之间的潜在关联,以制定有效的治疗策略。
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Exploring ocular disorders in Parkinson's disease: A comprehensive review and future perspectives.

Parkinson's disease (PD) is a multifaceted neurodegenerative disorder characterized by predominantly motor symptoms. However, recent research has broadened our understanding of PD by revealing its impact on non-motor functions, including ocular manifestations. This review explored the intricate relationship between PD and ocular health, shedding light on the mechanisms underlying common ocular diseases such as dry eye disease, cataract, glaucoma, age-related macular degeneration, and diabetic retinopathy. It also underscores the importance of recognizing ocular manifestations as potential early markers of PD, as well as their impact on patients' daily activities, necessitating prompt identification and intervention to prevent complications and enhance the overall quality of life. Furthermore, future research should prioritize unraveling the potential association between PD and other prevalent ocular diseases, such as myopia, to formulate effective treatment strategies.

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来源期刊
Experimental eye research
Experimental eye research 医学-眼科学
CiteScore
6.80
自引率
5.90%
发文量
323
审稿时长
66 days
期刊介绍: The primary goal of Experimental Eye Research is to publish original research papers on all aspects of experimental biology of the eye and ocular tissues that seek to define the mechanisms of normal function and/or disease. Studies of ocular tissues that encompass the disciplines of cell biology, developmental biology, genetics, molecular biology, physiology, biochemistry, biophysics, immunology or microbiology are most welcomed. Manuscripts that are purely clinical or in a surgical area of ophthalmology are not appropriate for submission to Experimental Eye Research and if received will be returned without review.
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