Lidia Bieniasz, Wojciech Domka, David Aebisher, Dorota Bartusik-Aebisher
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Photodynamic Therapy as a Future Method in the Treatment of Parotid Gland Tumor: A Review.
Photodynamic therapy (PDT) is emerging as a promising treatment for many diseases. This non-invasive approach uses photosensitizing agents and light to selectively destroy abnormal cells, providing a valuable alternative to traditional treatments. Scientists are investigating the use of PDT in various areas of the head, and their work is focused on a growing number of new discoveries and methods for treating cancer. We have analyzed the use of photodynamic therapy in the treatment of head and neck cancer (HNC) and present the latest advances in this field, with particular emphasis on its effectiveness in improving the long-term quality of life of patients with HNC. The effectiveness of PDT in the treatment of cancer depends largely on the depth of the tumor location. PDT is particularly useful in the treatment of early diagnosed cancers and superficial tumors. Many head and neck tumors are ideal candidates for this therapy due to the possibility of precise assessment of the lesions and the provision of adequate irradiation in these locations. PDT is currently considered a revolutionary, modern form of cancer therapy. A significant advantage of PDT is that cells do not develop resistance to singlet oxygen, which makes this method extremely effective. Although this method is safe, the limited depth of light penetration limits its use in the treatment of advanced stages of cancer.