有肝转移的老年结肠癌患者死于心脏病的风险因素

Q2 Medicine Asian Pacific Journal of Cancer Prevention Pub Date : 2024-12-01 DOI:10.31557/APJCP.2024.25.12.4217

Yuan Wu, Min-Hang Zhou

{"title":"有肝转移的老年结肠癌患者死于心脏病的风险因素","authors":"Yuan Wu, Min-Hang Zhou","doi":"10.31557/APJCP.2024.25.12.4217","DOIUrl":null,"url":null,"abstract":"Background: Colon cancer is one of the most frequently diagnosed cancers worldwide. The study aimed to identify the risk factors of death from heart disease in the elderly colon cancer patients with liver metastasis.Methods: All data of the retrospective study were retrieved from database of the Surveillance, Epidemiology, and End Results between 2000 and 2020. Odds ratio (OR) and the corresponding 95% confidence intervals (CIs) were calculated by using logistic regression model.Results: A total of 14322 elderly colon cancer patients with liver metastasis were identified. Out of them, 288 cases died of heart diseases, and 2001 cases were alive. In multivariate logistic analysis, the significant predictors for heart disease death were old age (OR = 1.06, p = 0.000), other histologic type besides adenocarcinoma (OR = 1.68, p = 0.004) and tumor size ≥ 5cm (OR = 1.89, p = 0.000). The protective factors were metastases besides liver (OR = 0.70, p = 0.027), surgery (OR = 0.64, p = 0.001) and chemotherapy (OR = 0.23, p = 0.000).Conclusion: Among elderly colon cancer with liver metastases, it is crucial to identify the risk factors and adopt preventive methods and appropriate treatment, which may enhance the quality of patient care and prolong patients' survival.","PeriodicalId":55451,"journal":{"name":"Asian Pacific Journal of Cancer Prevention","volume":"25 12","pages":"4217-4221"},"PeriodicalIF":0.0000,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Risk Factors for Death from Heart Disease in Elderly Colon Cancer Patients with Liver Metastasis.\",\"authors\":\"Yuan Wu, Min-Hang Zhou\",\"doi\":\"10.31557/APJCP.2024.25.12.4217\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Background: Colon cancer is one of the most frequently diagnosed cancers worldwide. The study aimed to identify the risk factors of death from heart disease in the elderly colon cancer patients with liver metastasis.Methods: All data of the retrospective study were retrieved from database of the Surveillance, Epidemiology, and End Results between 2000 and 2020. Odds ratio (OR) and the corresponding 95% confidence intervals (CIs) were calculated by using logistic regression model.Results: A total of 14322 elderly colon cancer patients with liver metastasis were identified. Out of them, 288 cases died of heart diseases, and 2001 cases were alive. In multivariate logistic analysis, the significant predictors for heart disease death were old age (OR = 1.06, p = 0.000), other histologic type besides adenocarcinoma (OR = 1.68, p = 0.004) and tumor size ≥ 5cm (OR = 1.89, p = 0.000). The protective factors were metastases besides liver (OR = 0.70, p = 0.027), surgery (OR = 0.64, p = 0.001) and chemotherapy (OR = 0.23, p = 0.000).Conclusion: Among elderly colon cancer with liver metastases, it is crucial to identify the risk factors and adopt preventive methods and appropriate treatment, which may enhance the quality of patient care and prolong patients' survival.\",\"PeriodicalId\":55451,\"journal\":{\"name\":\"Asian Pacific Journal of Cancer Prevention\",\"volume\":\"25 12\",\"pages\":\"4217-4221\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-12-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Asian Pacific Journal of Cancer Prevention\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.31557/APJCP.2024.25.12.4217\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Asian Pacific Journal of Cancer Prevention","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.31557/APJCP.2024.25.12.4217","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"Medicine","Score":null,"Total":0}

引用次数: 0

摘要

背景：结肠癌是世界上最常见的癌症之一。本研究旨在确定老年结肠癌肝转移患者心脏疾病死亡的危险因素。方法：回顾性研究的所有资料均来源于2000 - 2020年监测、流行病学和最终结果数据库。采用logistic回归模型计算优势比（OR）及相应的95%置信区间（ci）。结果：共发现老年结肠癌肝转移患者14322例。其中288人死于心脏病，2001人存活。在多因素logistic分析中，心脏病死亡的显著预测因素为年龄（OR = 1.06, p = 0.000）、除腺癌外的其他组织学类型（OR = 1.68, p = 0.004）和肿瘤大小≥5cm （OR = 1.89, p = 0.000）。保护因素为肝外转移（OR = 0.70, p = 0.027）、手术（OR = 0.64, p = 0.001）和化疗（OR = 0.23, p = 0.000）。结论：在老年结肠癌肝转移患者中，识别危险因素，采取预防措施和适当治疗是提高患者护理质量，延长患者生存期的关键。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文

微信好友朋友圈 QQ好友复制链接

本刊更多论文

Risk Factors for Death from Heart Disease in Elderly Colon Cancer Patients with Liver Metastasis.

Background: Colon cancer is one of the most frequently diagnosed cancers worldwide. The study aimed to identify the risk factors of death from heart disease in the elderly colon cancer patients with liver metastasis.

Methods: All data of the retrospective study were retrieved from database of the Surveillance, Epidemiology, and End Results between 2000 and 2020. Odds ratio (OR) and the corresponding 95% confidence intervals (CIs) were calculated by using logistic regression model.

Results: A total of 14322 elderly colon cancer patients with liver metastasis were identified. Out of them, 288 cases died of heart diseases, and 2001 cases were alive. In multivariate logistic analysis, the significant predictors for heart disease death were old age (OR = 1.06, p = 0.000), other histologic type besides adenocarcinoma (OR = 1.68, p = 0.004) and tumor size ≥ 5cm (OR = 1.89, p = 0.000). The protective factors were metastases besides liver (OR = 0.70, p = 0.027), surgery (OR = 0.64, p = 0.001) and chemotherapy (OR = 0.23, p = 0.000).

Conclusion: Among elderly colon cancer with liver metastases, it is crucial to identify the risk factors and adopt preventive methods and appropriate treatment, which may enhance the quality of patient care and prolong patients' survival.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Asian Pacific Journal of Cancer Prevention 医学-肿瘤学

CiteScore

2.80

自引率

0.00%

发文量

779

审稿时长

3 months

期刊介绍： Cancer is a very complex disease. While many aspects of carcinoge-nesis and oncogenesis are known, cancer control and prevention at the community level is however still in its infancy. Much more work needs to be done and many more steps need to be taken before effective strategies are developed. The multidisciplinary approaches and efforts to understand and control cancer in an effective and efficient manner, require highly trained scientists in all branches of the cancer sciences, from cellular and molecular aspects to patient care and palliation. The Asia Pacific Organization for Cancer Prevention (APOCP) and its official publication, the Asia Pacific Journal of Cancer Prevention (APJCP), have served the community of cancer scientists very well and intends to continue to serve in this capacity to the best of its abilities. One of the objectives of the APOCP is to provide all relevant and current scientific information on the whole spectrum of cancer sciences. They aim to do this by providing a forum for communication and propagation of original and innovative research findings that have relevance to understanding the etiology, progression, treatment, and survival of patients, through their journal. The APJCP with its distinguished, diverse, and Asia-wide team of editors, reviewers, and readers, ensure the highest standards of research communication within the cancer sciences community across Asia as well as globally. The APJCP publishes original research results under the following categories: -Epidemiology, detection and screening. -Cellular research and bio-markers. -Identification of bio-targets and agents with novel mechanisms of action. -Optimal clinical use of existing anti-cancer agents, including combination therapies. -Radiation and surgery. -Palliative care. -Patient adherence, quality of life, satisfaction. -Health economic evaluations.