炎症性肠病患者的无子女——来自前瞻性多中心瑞士IBD队列研究的数据

Munazza Marium, Muhammad Maaz, Aashish Kumar
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摘要

本研究调查了炎症性肠病(IBD)患者的无子女和不孕症。值得注意的是,该研究揭示了与性别和特定IBD亚型相关的有趣模式。在克罗恩病(CD)的女性患者中,与一般瑞士人群相比,观察到更高的无子女率。这一发现引发了关于乳糜泻对生殖健康影响的问题,包括疾病严重程度和治疗方案等因素。相反,患有溃疡性结肠炎(UC)的妇女表现出与一般人群相似的稳定的无子女率。UC作为一种独特的IBD亚型,受疾病位置和持续时间的影响,可能对生育能力有不同的影响。医疗保健提供者应解决IBD患者的生殖问题,强调生育咨询和量身定制的管理策略。未来的研究应该探索药物对生育结果的影响,而纵向研究可以增强我们对这一不断变化的景观的理解。总之,认识到IBD患者面临的独特挑战,使临床医生能够提供整合疾病控制和计划生育的整体护理,这需要专家和患者之间的合作。
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Childlessness in Patients with Inflammatory Bowel Disease - Data from the Prospective Multi-center Swiss IBD Cohort Study.

This study investigates childlessness and infertility in individuals diagnosed with inflammatory bowel disease (IBD). Notably, the research reveals intriguing patterns related to gender and specific IBD subtypes. Among female patients with Crohn's disease (CD), a higher childlessness rate is observed compared to the general Swiss population. This finding prompts questions about CD's impact on reproductive health, including factors such as disease severity and treatment regimens. Conversely, women with ulcerative colitis (UC) exhibit a stable childlessness rate similar to the general population. UC, as a distinct IBD subtype, may have varying effects on fertility, influenced by disease location and duration. Healthcare providers should address reproductive concerns in IBD patients, emphasizing fertility counseling and tailored management strategies. Future research should explore medication effects on fertility outcomes, and longitudinal studies can enhance our understanding of this evolving landscape. In summary, recognizing the unique challenges faced by IBD patients allows clinicians to provide holistic care that integrates disease control and family planning, necessitating collaboration among specialists and patients.

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