异体造血干细胞移植后侵袭性真菌感染的研究进展综述

Zhong-Yu Li, Yan-Ping Wu, Xue Bai, Jia-Jia Li
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引用次数: 0

摘要

同种异体造血干细胞移植(Allogeneic hematopoietic stem cell transplantation, alloo - hsct)是恶性血液病的主要治疗方法之一。随着移植技术的不断完善和普及,为血液恶性肿瘤患者延长生命、提高生存率带来了希望。然而,术后侵袭性真菌感染(IFI)是最常见的感染并发症,也是导致死亡的主要原因,早期诊断困难,死亡率极高。本文综述了与术后IFI相关的念珠菌、曲霉菌和毛霉菌的病原类型、诊断方法、高危因素及治疗方案等方面的最新研究进展,以期为提高术后IFI的早期诊断率和治疗效果提供参考。
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[Research Progress on Invasive Fungal Infection after Allogeneic Hematopoietic Stem Cell Transplantation --Review].

Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is one of the main treatment methods for hematological malignancies. With the continuous improvement and popularization of transplantation technology, it has brought hope for prolonging the lives and improving the survival rate of patients with hematological malignancies. However, postoperative invasive fungal infection (IFI) is the most common infectious complication and the main cause of death, with difficult early diagnosis and extremely high mortality. This paper summarizes the latest research progress on the pathogenic types, diagnostic methods, high-risk factors and treatment regimen of Candida, Aspergillus and Mucor associated with postoperative IFI, which is expected to provide references for improving the early diagnosis rate and treatment effectiveness of postoperative IFI.

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来源期刊
中国实验血液学杂志
中国实验血液学杂志 Medicine-Medicine (all)
CiteScore
0.40
自引率
0.00%
发文量
7331
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