永久性腹膜胸膜导尿管作为恶性腹水姑息性治疗的建立。

IF 1 4区 医学 Q3 MEDICINE, GENERAL & INTERNAL Danish medical journal Pub Date : 2024-11-12 DOI:10.61409/A02240098
Marie Riis Mortensen, Tue Duy Ngyuen, Hans Henrik Madsen, Michelle Meier
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引用次数: 0

摘要

难治性恶性腹水(RMA)是终末期癌症疾病的一种表现,由于症状负担和需要反复住院,对生活质量产生重大影响。我们之前描述了永久性胸膜导管的植入作为RMA的治疗方法。本研究旨在评估和描述我们迄今为止在最大队列中使用永久性胸膜导管系统的经验。方法:2015 - 2021年连续97例患者行PleurX导管植入术。我们使用患者的医疗记录检索患者和手术的回顾性数据。结果:96例(99%)种植成功,所有患者症状缓解。6例患者(6%)出现轻微或中度不良事件:3例因感染,2例因渗漏,1例因低血压。平均剩余寿命为77天。结论:永久性胸膜导管植入术是一种安全有效的治疗RMA的方法。我们强调通过植入永久腹膜导管早期发现和干预RMA管理的重要性。资金:没有。试验注册:不相关。
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Establishment of permanent peritoneal PleurX catheter as palliative treatment of malignant ascites.

Introduction: Refractory malignant ascites (RMA) is a manifestation of end-stage cancer disease with a major impact on quality of life due to the symptom burden and need for repeated hospitalisations. We previously described the implantation of the permanent PleurX catheter as a treatment of RMA. The present study aimed to evaluate and describe our experience with the permanent PleurX catheter system in the largest cohort to date.

Methods: A total of 97 consecutive patients had a PleurX catheter implanted from 2015 to 2021. We retrieved retrospective data on patients and procedures using the patient's medical records.

Results: A total of 96 (99%) of implantations were successful, and all patients had symptom relief. Six patients (6%) experienced minor or moderate adverse events: three due to infection, two due to leakage and one because of hypotension. The mean residual lifetime was 77 days.

Conclusions: We established that implantation of the permanent peritoneal PleurX catheter is a safe and efficient treatment of RMA. We emphasise the importance of early detection and intervention in the management of RMA by implantation of a permanent peritoneal catheter.

Funding: None.

Trial registration: Not relevant.

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来源期刊
Danish medical journal
Danish medical journal MEDICINE, GENERAL & INTERNAL-
CiteScore
2.30
自引率
6.20%
发文量
78
审稿时长
3-8 weeks
期刊介绍: The Danish Medical Journal (DMJ) is a general medical journal. The journal publish original research in English – conducted in or in relation to the Danish health-care system. When writing for the Danish Medical Journal please remember target audience which is the general reader. This means that the research area should be relevant to many readers and the paper should be presented in a way that most readers will understand the content. DMJ will publish the following articles: • Original articles • Protocol articles from large randomized clinical trials • Systematic reviews and meta-analyses • PhD theses from Danish faculties of health sciences • DMSc theses from Danish faculties of health sciences.
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