Cedric Agossah, Julien Marie, Yasmine Bendoukha, Cecile Vallet, Jacques Brouard, David Brossier
{"title":"首次发生细支气管炎的严重程度增加了发生哮喘症状的风险。","authors":"Cedric Agossah, Julien Marie, Yasmine Bendoukha, Cecile Vallet, Jacques Brouard, David Brossier","doi":"10.1111/apa.17565","DOIUrl":null,"url":null,"abstract":"<p><strong>Aim: </strong>The relationship between bronchiolitis and asthma is complex. We assessed whether patients admitted to a paediatric intensive care unit (PICU) with bronchiolitis had a greater risk of developing asthma than patients admitted to a paediatric ward.</p><p><strong>Methods: </strong>We retrospectively included children under 1 year of age, who were hospitalised for bronchiolitis for the first time at the University Hospital of Caen, France, between 2010 and 2014. The children were divided into two groups: 89 were admitted to the paediatric ward and 89 were admitted to the PICU. We wanted to assess which group developed more asthma before 6 years of age. The Global Initiative for Asthma definition was used.</p><p><strong>Results: </strong>The median age of the 178 children (55% boys) was 32 (interquartile range 19-56) days. We found that 35% of the PICU group and 19% of the ward group had asthma at 6 years of age. The mean onset of symptoms was 3 years earlier in the PICU group than the ward group (p < 0.01). Both these findings were significant.</p><p><strong>Conclusion: </strong>The severity of the first episode of bronchiolitis increased the risk of developing asthma symptoms. Regular follow-ups are suggested for infants admitted to PICUs for bronchiolitis.</p>","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":2.4000,"publicationDate":"2025-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The severity of the first occurrence of bronchiolitis increased the risk of developing asthma symptoms.\",\"authors\":\"Cedric Agossah, Julien Marie, Yasmine Bendoukha, Cecile Vallet, Jacques Brouard, David Brossier\",\"doi\":\"10.1111/apa.17565\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Aim: </strong>The relationship between bronchiolitis and asthma is complex. We assessed whether patients admitted to a paediatric intensive care unit (PICU) with bronchiolitis had a greater risk of developing asthma than patients admitted to a paediatric ward.</p><p><strong>Methods: </strong>We retrospectively included children under 1 year of age, who were hospitalised for bronchiolitis for the first time at the University Hospital of Caen, France, between 2010 and 2014. The children were divided into two groups: 89 were admitted to the paediatric ward and 89 were admitted to the PICU. We wanted to assess which group developed more asthma before 6 years of age. The Global Initiative for Asthma definition was used.</p><p><strong>Results: </strong>The median age of the 178 children (55% boys) was 32 (interquartile range 19-56) days. We found that 35% of the PICU group and 19% of the ward group had asthma at 6 years of age. The mean onset of symptoms was 3 years earlier in the PICU group than the ward group (p < 0.01). Both these findings were significant.</p><p><strong>Conclusion: </strong>The severity of the first episode of bronchiolitis increased the risk of developing asthma symptoms. Regular follow-ups are suggested for infants admitted to PICUs for bronchiolitis.</p>\",\"PeriodicalId\":55562,\"journal\":{\"name\":\"Acta Paediatrica\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":2.4000,\"publicationDate\":\"2025-01-02\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Acta Paediatrica\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1111/apa.17565\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"PEDIATRICS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Acta Paediatrica","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1111/apa.17565","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"PEDIATRICS","Score":null,"Total":0}
The severity of the first occurrence of bronchiolitis increased the risk of developing asthma symptoms.
Aim: The relationship between bronchiolitis and asthma is complex. We assessed whether patients admitted to a paediatric intensive care unit (PICU) with bronchiolitis had a greater risk of developing asthma than patients admitted to a paediatric ward.
Methods: We retrospectively included children under 1 year of age, who were hospitalised for bronchiolitis for the first time at the University Hospital of Caen, France, between 2010 and 2014. The children were divided into two groups: 89 were admitted to the paediatric ward and 89 were admitted to the PICU. We wanted to assess which group developed more asthma before 6 years of age. The Global Initiative for Asthma definition was used.
Results: The median age of the 178 children (55% boys) was 32 (interquartile range 19-56) days. We found that 35% of the PICU group and 19% of the ward group had asthma at 6 years of age. The mean onset of symptoms was 3 years earlier in the PICU group than the ward group (p < 0.01). Both these findings were significant.
Conclusion: The severity of the first episode of bronchiolitis increased the risk of developing asthma symptoms. Regular follow-ups are suggested for infants admitted to PICUs for bronchiolitis.
期刊介绍:
Acta Paediatrica is a peer-reviewed monthly journal at the forefront of international pediatric research. It covers both clinical and experimental research in all areas of pediatrics including:
neonatal medicine
developmental medicine
adolescent medicine
child health and environment
psychosomatic pediatrics
child health in developing countries