撤回:amp激酶抑制剂Dorsomorphin通过靶向Akt/mTOR通路降低结直肠癌细胞的增殖和迁移行为。

IF 3.7 3区 生物学 Q2 BIOCHEMISTRY & MOLECULAR BIOLOGY IUBMB Life Pub Date : 2025-01-05 DOI:10.1002/iub.2941
{"title":"撤回:amp激酶抑制剂Dorsomorphin通过靶向Akt/mTOR通路降低结直肠癌细胞的增殖和迁移行为。","authors":"","doi":"10.1002/iub.2941","DOIUrl":null,"url":null,"abstract":"<p>RETRACTION: S. Ghanaatgar-Kasbi, F. Amerizadeh, F. Rahmani, S. M. Hassanian, M. Khazaei, G. A. Ferns and A. Avan, “Amp-Kinase Inhibitor Dorsomorphin Reduces the Proliferation and Migration Behavior of Colorectal Cancer Cells by Targeting the Akt/mTOR Pathway,” <i>IUBMB Life</i> 71, no. 12 (2019): 1929–1936, https://doi.org/10.1002/iub.2136.</p><p>The above article, published online on 30 July 2019 in Wiley Online Library (wileyonlinelibrary.com), has been retracted by agreement between the journal Editor-in-Chief, Efstathios S. Gonos; International Union of Biochemistry and Molecular Biology; and Wiley Periodicals LLC. The retraction has been agreed following an investigation into concerns raised by a third party which revealed that the TBHP image and the Dorso 5μM image in Figure 3b contained an overlap with images published elsewhere by some of the same authors. In both instances of duplication, the images were used to represent different experimental conditions. Furthermore, the western blot in Figure 4D has been inappropriately edited and there is evidence that the bands have been spliced without clearly marking the splice sites. The authors provided an explanation and some data but this was not considered sufficient to address the concerns. As a result, the editors have lost confidence in the data presented and consider the conclusions substantially compromised. The authors disagree with the retraction.</p>","PeriodicalId":14728,"journal":{"name":"IUBMB Life","volume":"77 1","pages":""},"PeriodicalIF":3.7000,"publicationDate":"2025-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/iub.2941","citationCount":"0","resultStr":"{\"title\":\"RETRACTION: Amp-Kinase Inhibitor Dorsomorphin Reduces the Proliferation and Migration Behavior of Colorectal Cancer Cells by Targeting the Akt/mTOR Pathway\",\"authors\":\"\",\"doi\":\"10.1002/iub.2941\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p>RETRACTION: S. Ghanaatgar-Kasbi, F. Amerizadeh, F. Rahmani, S. M. Hassanian, M. Khazaei, G. A. Ferns and A. Avan, “Amp-Kinase Inhibitor Dorsomorphin Reduces the Proliferation and Migration Behavior of Colorectal Cancer Cells by Targeting the Akt/mTOR Pathway,” <i>IUBMB Life</i> 71, no. 12 (2019): 1929–1936, https://doi.org/10.1002/iub.2136.</p><p>The above article, published online on 30 July 2019 in Wiley Online Library (wileyonlinelibrary.com), has been retracted by agreement between the journal Editor-in-Chief, Efstathios S. Gonos; International Union of Biochemistry and Molecular Biology; and Wiley Periodicals LLC. The retraction has been agreed following an investigation into concerns raised by a third party which revealed that the TBHP image and the Dorso 5μM image in Figure 3b contained an overlap with images published elsewhere by some of the same authors. In both instances of duplication, the images were used to represent different experimental conditions. Furthermore, the western blot in Figure 4D has been inappropriately edited and there is evidence that the bands have been spliced without clearly marking the splice sites. The authors provided an explanation and some data but this was not considered sufficient to address the concerns. As a result, the editors have lost confidence in the data presented and consider the conclusions substantially compromised. The authors disagree with the retraction.</p>\",\"PeriodicalId\":14728,\"journal\":{\"name\":\"IUBMB Life\",\"volume\":\"77 1\",\"pages\":\"\"},\"PeriodicalIF\":3.7000,\"publicationDate\":\"2025-01-05\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://onlinelibrary.wiley.com/doi/epdf/10.1002/iub.2941\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"IUBMB Life\",\"FirstCategoryId\":\"99\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1002/iub.2941\",\"RegionNum\":3,\"RegionCategory\":\"生物学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"BIOCHEMISTRY & MOLECULAR BIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"IUBMB Life","FirstCategoryId":"99","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/iub.2941","RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"BIOCHEMISTRY & MOLECULAR BIOLOGY","Score":null,"Total":0}
引用次数: 0
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
RETRACTION: Amp-Kinase Inhibitor Dorsomorphin Reduces the Proliferation and Migration Behavior of Colorectal Cancer Cells by Targeting the Akt/mTOR Pathway

RETRACTION: S. Ghanaatgar-Kasbi, F. Amerizadeh, F. Rahmani, S. M. Hassanian, M. Khazaei, G. A. Ferns and A. Avan, “Amp-Kinase Inhibitor Dorsomorphin Reduces the Proliferation and Migration Behavior of Colorectal Cancer Cells by Targeting the Akt/mTOR Pathway,” IUBMB Life 71, no. 12 (2019): 1929–1936, https://doi.org/10.1002/iub.2136.

The above article, published online on 30 July 2019 in Wiley Online Library (wileyonlinelibrary.com), has been retracted by agreement between the journal Editor-in-Chief, Efstathios S. Gonos; International Union of Biochemistry and Molecular Biology; and Wiley Periodicals LLC. The retraction has been agreed following an investigation into concerns raised by a third party which revealed that the TBHP image and the Dorso 5μM image in Figure 3b contained an overlap with images published elsewhere by some of the same authors. In both instances of duplication, the images were used to represent different experimental conditions. Furthermore, the western blot in Figure 4D has been inappropriately edited and there is evidence that the bands have been spliced without clearly marking the splice sites. The authors provided an explanation and some data but this was not considered sufficient to address the concerns. As a result, the editors have lost confidence in the data presented and consider the conclusions substantially compromised. The authors disagree with the retraction.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
IUBMB Life
IUBMB Life 生物-生化与分子生物学
CiteScore
10.60
自引率
0.00%
发文量
109
审稿时长
4-8 weeks
期刊介绍: IUBMB Life is the flagship journal of the International Union of Biochemistry and Molecular Biology and is devoted to the rapid publication of the most novel and significant original research articles, reviews, and hypotheses in the broadly defined fields of biochemistry, molecular biology, cell biology, and molecular medicine.
期刊最新文献
Upstream transcription factor 1 suppresses laryngeal squamous cell carcinoma progression through transcriptional activation of junctional adhesion molecule 3 The cGAS-STING-related signature affects the prognosis of colorectal cancer through its regulation of multiple immune cells Issue Information Histone demethylase LSD1 promotes castration-resistant prostate cancer by causing widespread gene expression derangements Purification and validation of asparaginyl-tRNA synthetase heterodimer with indistinguishable subunits
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1