Kaitlynne Y Pak, Alberto Nunez, Harsh Patel, Allen S Ho, Jon Mallen-St Clair
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引用次数: 0
摘要
背景:在游离皮瓣重建中,甲状腺上动脉作为受体血管理论上可能会影响甲状腺功能。本研究旨在评估STA的使用是否会对甲状腺功能产生不良影响。方法:回顾性分析101例头颈部再造术的临床资料。术后1年内复查甲状腺功能检查。结果:40例患者采用STA。STA组TSH水平显著高于非STA组(7.34 vs 2.87 mU/L, p = 0.02)。STA组约27.5%出现亚临床术后甲状腺功能减退,17.5%需要补充新的左旋甲状腺素。结论:据我们所知,这是第一个评估STA作为受体血管对术后甲状腺功能影响的研究。虽然我们发现使用STA后平均TSH有统计学意义上的差异,但平均TSH/FT4值是亚临床的。术后监测甲状腺功能减退是必要的在这一人群。
Use of the Superior Thyroid Artery as a Recipient Artery in Head and Neck Free Flap Reconstruction: Effects on Post-Operative Hypothyroidism.
Background: The superior thyroid artery (STA) as a recipient vessel in free flap reconstruction may theoretically impact thyroid function. This study aimed to assess whether the use of the STA has an adverse effect on thyroid function.
Methods: Retrospective review of 101 head and neck reconstructive cases. Thyroid function tests were reviewed within 1 year of surgery.
Results: The STA was used in 40 cases. The STA cohort had significantly higher TSH levels than the non-STA cohort (7.34 v. 2.87 mU/L, p = 0.02). About 27.5% developed subclinical post-operative hypothyroidism and 17.5% required new levothyroxine supplementation in the STA group.
Conclusion: This represents the first study to our knowledge assessing the impact of the STA as a recipient vessel on postoperative thyroid function. While we found a statistically significant difference in average TSH after using the STA, the average TSH/FT4 values were subclinical. Post-operative monitoring for hypothyroidism is warranted in this population.
期刊介绍:
Head & Neck is an international multidisciplinary publication of original contributions concerning the diagnosis and management of diseases of the head and neck. This area involves the overlapping interests and expertise of several surgical and medical specialties, including general surgery, neurosurgery, otolaryngology, plastic surgery, oral surgery, dermatology, ophthalmology, pathology, radiotherapy, medical oncology, and the corresponding basic sciences.