2023年1月至6月华盛顿州金县成人轮状病毒腹泻感染暴发

Jimmy Ma, Raaka G Kumbhakar, Amanda Casto, Eric J Chow, Janet A Englund, Rashi Gautam, Jose Jaimes, Jacqueline E Tate, Sarah Smart, Nandita S Mani, Seth A Cohen, Abby Hussein, Krista Rietberg, Chloe Bryson-Cahn, Ferric C Fang
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引用次数: 0

摘要

轮状病毒是儿童腹泻的主要原因,但在成人中却鲜为人知。我们描述了2023年1月至6月发生在华盛顿金县成人中轮状病毒爆发的临床、流行病学和基因型特征。2023年的成人轮状病毒发病率是2022年同期的10倍(5%对0.5%)。病情轻微。G9P[4]是美国一种罕见的非疫苗株,是主要的基因型。基因分型提示从儿童开始外溢,随后在成人中传播。我们的研究强调了在疫情期间进行常规检测和基因分型的好处,以便监测、跟踪和了解对疫苗接种的影响。
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Outbreak of Rotavirus Diarrheal Infection among Adults in King County, Washington, January-June 2023
Rotavirus is a leading cause of diarrhea among children but less known as a cause among adults. We describe clinical, epidemiologic, and genotype characteristics of a rotavirus outbreak among adults in King County, Washington occurring January-June 2023. Adult rotavirus incidence in 2023 was ten times higher than the same period in 2022 (5% versus 0.5% samples). Disease severity was mild. G9P[4], an uncommon, non-vaccine strain in USA, was the predominant genotype. Genotyping suggested spillover from children with subsequent spread among adults. Our study highlights benefits of routine testing and genotyping during outbreaks for surveillance, tracking, and understanding implications on vaccination.
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