XEN植入术后皮下色素沉着:一个病例系列。

IF 1.4 4区 医学 Q3 OPHTHALMOLOGY European Journal of Ophthalmology Pub Date : 2025-01-08 DOI:10.1177/11206721241310267
Filippo Tatti, Giuseppe Demarinis, Stefano Dore, Matteo Sacchi, Maurizio Fossarello, Enrico Peiretti, Giuseppe Giannaccare
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引用次数: 0

摘要

目的:评价XEN63植入术后体内色素沉着(IBP)的发生率及特点。方法:对三眼眼压不控制的XEN63植入术后滤过泡出现色素分散的病例进行回顾性分析。人口统计、临床和影像学数据来自医疗记录。结果:40例XEN植入术患者中有3例(平均年龄70.67岁)在术后12个月内出现IBP。IBP平均发病时间为50天(15 ~ 90天)。裂隙灯检查显示两种IBP模式:一种“弥漫性”模式(2例),水泡内有多个色素斑点;“点状”模式(1例),在装置的远端有一个点。as - oct成像证实了IBP的存在,在滤过泡的背景下表现为一个高反射斑。点状IBP患者出现远端XEN口梗阻,伴有泡功能下降。在一个病例中,弥漫性IBP发生在成功的针刺手术后。随访结束时,所有患者的IOP均低于21 mmHg。结论:XEN植入术后IBP的发展可能在不同的时间和模式下发生。IBP模式可以为气泡过滤功能提供有意义的线索。建议采用裂隙灯生物显微镜、IOP测量和AS-OCT成像进行适当的随访,以管理IBP相关的潜在并发症。
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"Intrableb pigmentation following XEN implantation: A case series".

Purpose: To evaluate the incidence and to describe the characteristics of the intrableb pigmentation (IBP) following XEN63 implantation.

Methods: Retrospective case series of three eyes presenting a pigment dispersion in the filtering bleb after a XEN63 implantation for uncontrolled IOP. Demographic, clinical and imaging data were obtained from medical records.

Results: Three out of 40 patients who underwent XEN implantation (average age 70.67 years) showed an IBP during the 12 months postoperative period. The mean time of IBP onset was 50 days (range, 15-90). The slit lamp examination showed two IBP patterns: a "diffuse" pattern (2 patients) with multiple spots of pigmentation inside the bleb; a "punctiform" pattern (1 patient), with a single spot at the distal end of the device. The AS-OCT imaging confirmed the presence of IBP appearing as a hyperreflective spot/s in the context of the filtering bleb. The patient with the punctiform IBP experienced a distal XEN ostium obstruction with a decrease in bleb function. In one case the diffuse IBP occurred after a successful needling procedure. All the patients' IOP reported at the end of the follow-up was below 21 mmHg.

Conclusion: The development of IBP might occur after XEN implantation in various times and with different patterns. The IBP pattern can provide meaningful clues on the bleb filtering function. A proper follow-up based on slit lamp biomicroscopy, IOP measurement, and AS-OCT imaging is recommended to manage potential complications related to IBP.

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来源期刊
CiteScore
3.60
自引率
0.00%
发文量
372
审稿时长
3-8 weeks
期刊介绍: The European Journal of Ophthalmology was founded in 1991 and is issued in print bi-monthly. It publishes only peer-reviewed original research reporting clinical observations and laboratory investigations with clinical relevance focusing on new diagnostic and surgical techniques, instrument and therapy updates, results of clinical trials and research findings.
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