手脚锻炼对乳腺癌患者周围神经病变和生活质量的影响:一项随机对照试验

IF 2.8 3区 医学 Q2 HEALTH CARE SCIENCES & SERVICES Supportive Care in Cancer Pub Date : 2025-01-08 DOI:10.1007/s00520-025-09145-x
Neşe Uysal, Filiz Ünal Toprak
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引用次数: 0

摘要

目的:周围神经病变是患者最具破坏性的症状之一。支持性和整体护理干预措施对帮助这些患者至关重要。本研究的目的是确定手脚运动对化疗诱导的乳腺癌女性周围神经病变和生活质量的影响。方法:本随机对照试验研究的样本包括79名在医院接受紫杉烷组化疗的乳腺癌妇女。诊断为1级或更高级别周围神经病变的妇女被纳入研究。女性被分成三组,分别是按摩球组、压力球组和对照组。手和脚的锻炼持续8周。使用信息表、不良事件通用术语标准和欧洲癌症研究和治疗组织生活质量问卷收集数据。结果:与对照组相比,按摩球组和压力球运动组的神经病变严重程度均显著降低(p)。结论:乳腺癌患者接受神经毒性化疗后,通过简单的家庭运动可以缓解神经病变症状,提高生活质量。在化疗过程中,非药物的、适用的干预措施,如手脚练习,可纳入患者教育和护理实践。试验注册:ClinicalTrails.gov(注册号:NCT06055088)。于2023年6月1日注册)。
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The effect of hand and foot exercises on peripheral neuropathy and quality of life in women with breast cancer: a randomized controlled trial.

Purpose: Peripheral neuropathy is one of the most devastating symptoms experienced by the patients. Supportive and holistic care interventions are crucial to help these patients. The aim of this study is to determine the effects of hand and foot exercises on chemotherapy-induced peripheral neuropathy and quality of life in women with breast cancer.

Methods: The sample of this randomized controlled trial study consisted of 79 women with breast cancer who underwent taxane-group chemotherapy in a hospital. The women diagnosed with grade 1 or higher peripheral neuropathy were included in the study. Women were divided into three groups as exercises with a massage ball, exercises with a stress ball, and control group. Hand and foot exercises last for 8 weeks. Data were collected using the Information Form, the Common Terminology Criteria for Adverse Events, and the European Organization for the Research and Treatment of Cancer Quality of Life Questionnaire.

Results: The severity of neuropathy decreased significantly in both massage ball and stress ball exercise groups compared to the control group (p < 0.05). The group and time interaction was statistically significant in fatigue, pain, and motor symptoms (p < 0.05).

Conclusion: Women with breast cancer who undergo neurotoxic chemotherapy are thought to alleviate neuropathy symptoms and enhance their quality of life through simple home-based exercises. Nonpharmacological, applicable interventions, such as hand-foot exercises, can be integrated into patient education and care practices during the chemotherapy process.

Trial registration: ClinicalTrails.gov (Registration number: NCT06055088. registered on 01 June 2023).

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来源期刊
Supportive Care in Cancer
Supportive Care in Cancer 医学-康复医学
CiteScore
5.70
自引率
9.70%
发文量
751
审稿时长
3 months
期刊介绍: Supportive Care in Cancer provides members of the Multinational Association of Supportive Care in Cancer (MASCC) and all other interested individuals, groups and institutions with the most recent scientific and social information on all aspects of supportive care in cancer patients. It covers primarily medical, technical and surgical topics concerning supportive therapy and care which may supplement or substitute basic cancer treatment at all stages of the disease. Nursing, rehabilitative, psychosocial and spiritual issues of support are also included.
期刊最新文献
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