一种新提出的内镜评分系统评估整个小肠和预测克罗恩病的预后。

IF 0.9 4区 医学 Q4 MEDICINE, RESEARCH & EXPERIMENTAL Nagoya Journal of Medical Science Pub Date : 2024-11-01 DOI:10.18999/nagjms.86.4.608
Hitoshi Tanaka, Masanao Nakamura, Takeshi Yamamura, Keiko Maeda, Tsunaki Sawada, Eri Ishikawa, Takashi Hirose, Kota Uetsuki, Tadashi Iida, Yasuyuki Mizutani, Kentaro Yamao, Takuya Ishikawa, Yoji Ishizu, Kazuhiro Furukawa, Takashi Honda, Genta Uchida, Hiroki Kawashima
{"title":"一种新提出的内镜评分系统评估整个小肠和预测克罗恩病的预后。","authors":"Hitoshi Tanaka, Masanao Nakamura, Takeshi Yamamura, Keiko Maeda, Tsunaki Sawada, Eri Ishikawa, Takashi Hirose, Kota Uetsuki, Tadashi Iida, Yasuyuki Mizutani, Kentaro Yamao, Takuya Ishikawa, Yoji Ishizu, Kazuhiro Furukawa, Takashi Honda, Genta Uchida, Hiroki Kawashima","doi":"10.18999/nagjms.86.4.608","DOIUrl":null,"url":null,"abstract":"<p><p>Small bowel stenosis in patients with Crohn's disease leads to abdominal symptoms and can affect prognosis. The Simple Endoscopic Score for Crohn's Disease for the large bowel has been applied to the small bowel; however, stenosis scoring may be overestimated since it has a long diameter. This retrospective study aimed to devise a new endoscopic scoring system including the small bowel and evaluate whether it predicts the prognosis of Crohn's disease. The study included 103 patients with Crohn's disease at our hospital. We modified the Simple Endoscopic Score for Crohn's Disease and proposed a new scoring system; the modified applied Simple Endoscopic Score for Crohn's Disease was created by subtracting one point for stricture from the Simple Endoscopic Score for Crohn's Disease. Receiver operating characteristic curve analysis was performed to assess the accuracy of the modified applied score for Crohn's disease in predicting disease worsening within 1 year. Results were validated using the log-rank test. For the modified applied score, the area under the receiver operating characteristic curve for disease worsening within 1 year in 57 cases was 0.850. When the cutoff score was set to 9 points, the sensitivity and specificity were 72.7% and 80.6%, respectively. The log-rank test showed a significant difference (<i>P</i> = 0.027) in the risk of worsening within 1 year between the low (<9 points) and high (≥9 points) score groups. Thus, a higher modified applied Simple Endoscopic Score for Crohn's Disease may be associated with a significantly increased risk of disease worsening within 1 year.</p>","PeriodicalId":49014,"journal":{"name":"Nagoya Journal of Medical Science","volume":"86 4","pages":"608-619"},"PeriodicalIF":0.9000,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11704775/pdf/","citationCount":"0","resultStr":"{\"title\":\"A newly proposed endoscopic score system to evaluate the entire small bowel and predict the prognosis in Crohn's disease.\",\"authors\":\"Hitoshi Tanaka, Masanao Nakamura, Takeshi Yamamura, Keiko Maeda, Tsunaki Sawada, Eri Ishikawa, Takashi Hirose, Kota Uetsuki, Tadashi Iida, Yasuyuki Mizutani, Kentaro Yamao, Takuya Ishikawa, Yoji Ishizu, Kazuhiro Furukawa, Takashi Honda, Genta Uchida, Hiroki Kawashima\",\"doi\":\"10.18999/nagjms.86.4.608\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Small bowel stenosis in patients with Crohn's disease leads to abdominal symptoms and can affect prognosis. The Simple Endoscopic Score for Crohn's Disease for the large bowel has been applied to the small bowel; however, stenosis scoring may be overestimated since it has a long diameter. This retrospective study aimed to devise a new endoscopic scoring system including the small bowel and evaluate whether it predicts the prognosis of Crohn's disease. The study included 103 patients with Crohn's disease at our hospital. We modified the Simple Endoscopic Score for Crohn's Disease and proposed a new scoring system; the modified applied Simple Endoscopic Score for Crohn's Disease was created by subtracting one point for stricture from the Simple Endoscopic Score for Crohn's Disease. Receiver operating characteristic curve analysis was performed to assess the accuracy of the modified applied score for Crohn's disease in predicting disease worsening within 1 year. Results were validated using the log-rank test. For the modified applied score, the area under the receiver operating characteristic curve for disease worsening within 1 year in 57 cases was 0.850. When the cutoff score was set to 9 points, the sensitivity and specificity were 72.7% and 80.6%, respectively. The log-rank test showed a significant difference (<i>P</i> = 0.027) in the risk of worsening within 1 year between the low (<9 points) and high (≥9 points) score groups. Thus, a higher modified applied Simple Endoscopic Score for Crohn's Disease may be associated with a significantly increased risk of disease worsening within 1 year.</p>\",\"PeriodicalId\":49014,\"journal\":{\"name\":\"Nagoya Journal of Medical Science\",\"volume\":\"86 4\",\"pages\":\"608-619\"},\"PeriodicalIF\":0.9000,\"publicationDate\":\"2024-11-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11704775/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Nagoya Journal of Medical Science\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.18999/nagjms.86.4.608\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"MEDICINE, RESEARCH & EXPERIMENTAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nagoya Journal of Medical Science","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.18999/nagjms.86.4.608","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"MEDICINE, RESEARCH & EXPERIMENTAL","Score":null,"Total":0}
引用次数: 0

摘要

克罗恩病患者的小肠狭窄可导致腹部症状并影响预后。大肠克罗恩病简单内镜评分法已应用于小肠;然而,狭窄评分可能被高估,因为它的直径很长。本回顾性研究旨在设计一种包括小肠在内的新的内镜评分系统,并评估其是否能预测克罗恩病的预后。本研究包括我院103例克罗恩病患者。我们对克罗恩病简单内镜评分进行了改进,提出了一种新的评分系统;通过从克罗恩病简单内窥镜评分中减去狭窄1分,创建改良的适用于克罗恩病的简单内窥镜评分。进行受试者工作特征曲线分析,评估改良克罗恩病应用评分预测1年内病情恶化的准确性。使用log-rank检验对结果进行验证。修正应用评分后,57例患者1年内病情加重的受试者工作特征曲线下面积为0.850。当临界值设为9分时,敏感性为72.7%,特异性为80.6%。log-rank检验显示,低组和低组在1年内恶化的风险有显著差异(P = 0.027)。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
A newly proposed endoscopic score system to evaluate the entire small bowel and predict the prognosis in Crohn's disease.

Small bowel stenosis in patients with Crohn's disease leads to abdominal symptoms and can affect prognosis. The Simple Endoscopic Score for Crohn's Disease for the large bowel has been applied to the small bowel; however, stenosis scoring may be overestimated since it has a long diameter. This retrospective study aimed to devise a new endoscopic scoring system including the small bowel and evaluate whether it predicts the prognosis of Crohn's disease. The study included 103 patients with Crohn's disease at our hospital. We modified the Simple Endoscopic Score for Crohn's Disease and proposed a new scoring system; the modified applied Simple Endoscopic Score for Crohn's Disease was created by subtracting one point for stricture from the Simple Endoscopic Score for Crohn's Disease. Receiver operating characteristic curve analysis was performed to assess the accuracy of the modified applied score for Crohn's disease in predicting disease worsening within 1 year. Results were validated using the log-rank test. For the modified applied score, the area under the receiver operating characteristic curve for disease worsening within 1 year in 57 cases was 0.850. When the cutoff score was set to 9 points, the sensitivity and specificity were 72.7% and 80.6%, respectively. The log-rank test showed a significant difference (P = 0.027) in the risk of worsening within 1 year between the low (<9 points) and high (≥9 points) score groups. Thus, a higher modified applied Simple Endoscopic Score for Crohn's Disease may be associated with a significantly increased risk of disease worsening within 1 year.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Nagoya Journal of Medical Science
Nagoya Journal of Medical Science MEDICINE, RESEARCH & EXPERIMENTAL-
CiteScore
1.30
自引率
0.00%
发文量
65
审稿时长
>12 weeks
期刊介绍: The Journal publishes original papers in the areas of medical science and its related fields. Reviews, symposium reports, short communications, notes, case reports, hypothesis papers, medical image at a glance, video and announcements are also accepted. Manuscripts should be in English. It is recommended that an English check of the manuscript by a competent and knowledgeable native speaker be completed before submission.
期刊最新文献
Clinical characteristics of individuals stratified by the number of answered items on the 25-question Geriatric Locomotive Function Scale. Mycobacterium marinum infection successfully treated with oral administration of minocycline and thermotherapy. Delayed open-heart operation to remove migrated intracardiac inferior vena cava stents in a living donor liver transplantation recipient: a case report. A case of peribronchiolar metaplasia of the lung appearing as a solid nodule on computed tomography. Efficacy and safety of endovascular coil embolization for unruptured middle cerebral artery aneurysms: middle-term clinical and imaging outcomes with 3 years mean follow-up periods, a 16-year experience.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1