气候变化与眼表疾病。

Die Ophthalmologie Pub Date : 2025-01-01 Epub Date: 2025-01-07 DOI:10.1007/s00347-024-02167-6
A V Schilcher, G Geerling
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引用次数: 0

摘要

背景:眼表直接受到环境的影响。已经确定的眼表辐射有热、空气干燥、污染气体、细尘颗粒和紫外线辐射。方法:利用现有文献,探讨眼表常见病与各种环境因素的关系,并分析其多年来的发展情况。结果:干眼病和变应性结膜炎的流行病学研究表明,近年来干眼病和变应性结膜炎的发病率呈上升趋势。环境污染物已被确定为疾病诱因。此外,花粉季节延长和花粉浓度升高也是危险因素。在高紫外线照射人群中,翼状胬肉的患病率也较高。其他具有潜在环境发病机制的疾病有急性光性角膜炎、光性结膜炎和结膜恶性黑色素瘤。结论:对于眼表疾病,大型流行病学队列显示气候相关的发病率增加。预计在今后几十年里,与环境有关的有害物质将进一步增加。除了减缓气候变化的措施外,还应研究疾病发展的潜在机制和预防和治疗的新方法,如房间加湿、空气过滤器或带紫外线过滤器的隐形眼镜。
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[Climate change and ocular surface diseases].

Background: The ocular surface is directly exposed to environmental influences. Noxae that have already been identified for the ocular surface are heat, air dryness, pollutant gases, fine dust particles and ultraviolet radiation.

Methods: The current literature was used to investigate the relationship between frequent ocular surface diseases and various environmental factors and to analyze their development over the years.

Results: Epidemiological studies on dry eye disease and allergic conjunctivitis have shown an increase in the incidences in recent years. Environmental pollutants have been identified as disease triggers. In addition, the prolonged pollen season and increased pollen concentrations are also risk factors. There is also a higher prevalence of pterygium in population groups with high UV exposure. Other diseases with potential environmental pathogenesis are acute photokeratitis, photoconjunctivitis and malignant melanoma of the conjunctiva.

Conclusion: For ocular surface diseases, large epidemiological cohorts have shown climate-related increases in the incidence. A further increase in environmentally associated noxious substances can be expected in the coming decades. In addition to measures to mitigate climate change, the underlying mechanisms of disease development and new approaches to prevention and treatment, such as room humidification, air filters or contact lenses with UV filters, should be investigated.

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