先天性心脏手术患者的术中心脏骤停。

Morgan L. Brown MD, PhD , Steven J. Staffa MS , Phillip S. Adams DO , Lisa A. Caplan MD , Stephen J. Gleich MD , Jennifer L. Hernandez MD , Martina Richtsfeld MD , Lori Q. Riegger MD , David F. Vener MD , Quality and Safety Committee of the Congenital Cardiac Anesthesia Society
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引用次数: 0

摘要

目的:描述先天性心脏手术患者术中心脏骤停的情况。方法:查询美国胸外科学会先天性心脏外科数据库。采用单变量和多变量分析评估术中心脏骤停的预测因素。术中心脏骤停的单变量关系也与数据库中可用的结果进行了比较。结果:共有92764例患者出现麻醉不良事件,357例(0.38%)患者出现术中心脏骤停。术中心脏骤停的多变量预测因素包括年龄(优势比[OR], 0.98 /年;95%置信区间[CI], 0.97-0.99;P = 0.036),术前心脏骤停(P = 0.002),非胰岛素依赖型糖尿病(OR, 6.4;95% CI, 1.9-21.9, P = 0.003),增加胸外科学会-欧洲心胸外科协会(STAT)分类(OR, STAT 5 vs STAT 1;95% CI, 1.3-3.9, P = 0.003),紧急(OR, 2.0;95% CI, 1.6-2.6, P P P P P P P P P结论:术中心脏骤停发生率低;然而,它是患者围手术期发病率和死亡率的重要指标。
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Intraoperative cardiac arrest in patients undergoing congenital cardiac surgery

Objective

To describe intraoperative cardiac arrest in patients undergoing congenital heart surgery.

Methods

The Society of Thoracic Surgeons Congenital Heart Surgery Database was queried. Predictors of intraoperative cardiac arrest were assessed using univariate and multivariable analyses. The univariate relationship between intraoperative cardiac arrest was also compared with available outcomes in the database.

Results

A total of 92,764 cases had anesthesia adverse event data, and 357 patients (0.38%) had an intraoperative cardiac arrest. Multivariable predictors of an intraoperative cardiac arrest included age (odds ratio [OR], 0.98 per year; 95% confidence interval [CI], 0.97-0.99; P = .036), preoperative cardiac arrest (<48 hours) (OR, 9.6; 95% CI 6.3-14.6, P < .001), preoperative neurologic deficit (OR, 2.0; 95% CI, 1.3-3.1, P = .002), noninsulin-dependent diabetes mellitus (OR, 6.4; 95% CI, 1.9-21.9, P = .003), increasing Society of Thoracic Surgeons-European Association for Cardio-Thoracic Surgery (STAT) category (OR, 2.3 for STAT 5 vs STAT 1; 95% CI, 1.3-3.9, P = .003), urgent (OR, 2.0; 95% CI, 1.6-2.6, P < .001) or emergent surgery (OR, 3.1; 95% CI, 1.9-5.0, P < .001), and increasing length of total operating room time (OR, 1.2 per hour; 95% CI, 1.2-1.3, P < .001). Intraoperative cardiac arrest was associated with a greater 30-day mortality (14.6% vs 1.8%, P < .001). There were more morbidities in the intraoperative cardiac arrest group including postoperative neurologic deficits (12% vs 1.0%, P < .001), multisystem organ failure (5.9% vs 0.7%, P < .001), and greater rates of unplanned reoperation (19.3% vs 5.0%, P < .001) or interventional cardiac catheterization (7% vs 3.2%, P < .001).

Conclusions

The incidence of intraoperative cardiac arrest is low; however, it is an important indicator of significant patient perioperative morbidity and mortality.
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