隧道腹膜导管姑息性腹水引流并发症的相关危险因素

IF 3.9 3区 医学 Q1 GASTROENTEROLOGY & HEPATOLOGY Therapeutic Advances in Gastroenterology Pub Date : 2025-01-10 eCollection Date: 2025-01-01 DOI:10.1177/17562848241310183
Domenique Machnik, Sarah Fischer, Marcel Vetter, Ricarda Lamprecht-Bailer, Rachel Rouse-Merkel, Daniel Klett, Markus F Neurath, Deike Strobel, Sebastian Zundler, Sophie Haberkamp
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引用次数: 0

摘要

背景:医学上难治性腹水给姑息性疾病患者带来巨大痛苦。隧道腹膜导管已被确立为一种可行的治疗选择,允许在家庭护理设置患者控制穿刺。然而,尽管一系列并发症与这些引流有关,但迄今为止尚未确定并发症的危险因素。目的:探讨隧道式腹膜导管并发症的潜在危险因素。设计:回顾性观察队列研究。方法:单中心队列包括49例姑息性疾病患者,在三级医院接受57根隧道腹膜导管。结果:所有患者置管成功,严重并发症发生率低。我们的数据表明,在良性疾病患者中,当由经验不足的医生进行引流替代时,发生严重晚期并发症的风险更高。结论:隧道式腹膜导尿管是治疗晚期姑息性疾病患者症状性腹水的一种有效且安全的选择。对于患有良性疾病的患者,以及以前的导管切除或脱位后,应仔细考虑适应症。
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Risk factors associated with complications of palliative drainage of ascites with tunneled peritoneal catheters.

Background: Medically intractable ascites causes substantial distress in patients with palliative disease. Tunneled peritoneal catheters have been established as a feasible treatment option allowing patient-controlled paracentesis in a homecare setting. However, while a range of complications is associated with these drainages, risk factors for complications have not been identified so far.

Objectives: To explore potential risk factors associated with complications of tunneled peritoneal catheters.

Design: Retrospective observational cohort study.

Methods: Single-center cohort comprising 49 patients with palliative disease receiving 57 tunneled peritoneal catheters at a tertiary care hospital.

Results: Catheter placement was successful in all patients and associated with low numbers of severe complications. Our data suggest a higher risk for severe late complications in patients with benign disease, with drainage replacement, and when performed by less experienced physicians.

Conclusion: Tunneled peritoneal catheters are an effective and safe option to treat symptomatic ascites in patients with end-stage palliative disease. The indication should be carefully considered in patients with benign disease and after removal or dislocation of a previous catheter.

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来源期刊
Therapeutic Advances in Gastroenterology
Therapeutic Advances in Gastroenterology GASTROENTEROLOGY & HEPATOLOGY-
CiteScore
6.70
自引率
2.40%
发文量
103
审稿时长
15 weeks
期刊介绍: Therapeutic Advances in Gastroenterology is an open access journal which delivers the highest quality peer-reviewed original research articles, reviews, and scholarly comment on pioneering efforts and innovative studies in the medical treatment of gastrointestinal and hepatic disorders. The journal has a strong clinical and pharmacological focus and is aimed at an international audience of clinicians and researchers in gastroenterology and related disciplines, providing an online forum for rapid dissemination of recent research and perspectives in this area. The editors welcome original research articles across all areas of gastroenterology and hepatology. The journal publishes original research articles and review articles primarily. Original research manuscripts may include laboratory, animal or human/clinical studies – all phases. Letters to the Editor and Case Reports will also be considered.
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