儿童癌症幸存者的健康状况和慢性病与体育锻炼的关系。

IF 2.8 3区 医学 Q2 HEALTH CARE SCIENCES & SERVICES Supportive Care in Cancer Pub Date : 2025-01-15 DOI:10.1007/s00520-025-09157-7
Sanyukta K Janardan, Rebecca Williamson Lewis, Jordan Gilleland Marchak, Ann C Mertens, Karen E Effinger
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引用次数: 0

摘要

目的:儿童癌症幸存者(CCS)存在治疗相关晚期效应的风险。体育活动(PA)可以减少一些后期影响的风险,但在CCS中PA的发生率很低。我们的目的是确定幸存者健康状况和慢性疾病的存在如何与患者或代理报告的PA相关。方法:本研究对CCS患者(6-25岁,停药≥1年)进行了横断面、回顾性研究,将低PA定义为:结果:284例CCS患者中,71.8%报告低PA。总体、身体和心理健康状况的负面感知分别在5.6%、10.6%和15.9%的CCS中存在,慢性疾病的存在占49.7%。低PA与女性(p = 0.002)、身体(p = 0.01)和精神(p = 0.02)健康状况差直接相关,与复发/难治性疾病呈负相关(p = 0.03)。慢性疾病的存在与低PA无关(p = 0.68);然而,所有患有慢性移植物抗宿主病或视力障碍的CCS患者的PA均较低。结论:低PA是CCS的一个问题,尤其是女性,并与消极的身心健康感知有关。未来针对CCS的PA干预措施应解决感知到的身心健康问题,并将重点放在特定的高危亚群体上。
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The association of perceived health status and presence of chronic conditions with physical activity in childhood cancer survivors.

Purpose: Childhood cancer survivors (CCS) are at risk for therapy-related late effects. Physical activity (PA) can minimize some late effects risk, but rates of PA are low in CCS. We aimed to determine how perception of survivor health status and presence of chronic conditions are associated with patient- or proxy-reported PA.

Methods: This cross-sectional, retrospective study of CCS (6-25 years; ≥ 1 year off-therapy) defined low PA as < 5 days per week with ≥ 60 minutes/day of patient- or proxy-reported activity. Participants completed PROMIS Global Health questions assessing perceptions of overall, physical, and mental health. Presence of chronic conditions was abstracted from the health record and defined as ≥ 2 late effects. Multivariable logistic regressions were performed to identify associations between physical activity and health status or chronic conditions.

Results: Of 284 CCS, 71.8% reported low PA. Negative perceived overall, physical, and mental health status were present in 5.6%, 10.6%, and 15.9% of CCS, respectively, with presence of chronic conditions in 49.7%. Low PA was directly associated with female sex (p = 0.002) and poor physical (p = 0.01) and mental (p = 0.02) health status, and inversely associated with relapsed/refractory disease (p = 0.03). Presence of chronic conditions was not associated with low PA (p = 0.68); however, all CCS with chronic graft-versus-host disease or vision impairment had low PA.

Conclusion: Low PA is an issue for CCS, especially females, and is associated with negative perceived physical and mental health. Future PA interventions for CCS should address perceived physical and mental health, and focus on specific at-risk sub-groups.

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来源期刊
Supportive Care in Cancer
Supportive Care in Cancer 医学-康复医学
CiteScore
5.70
自引率
9.70%
发文量
751
审稿时长
3 months
期刊介绍: Supportive Care in Cancer provides members of the Multinational Association of Supportive Care in Cancer (MASCC) and all other interested individuals, groups and institutions with the most recent scientific and social information on all aspects of supportive care in cancer patients. It covers primarily medical, technical and surgical topics concerning supportive therapy and care which may supplement or substitute basic cancer treatment at all stages of the disease. Nursing, rehabilitative, psychosocial and spiritual issues of support are also included.
期刊最新文献
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