一名免疫力低下的成年人感染了散播的螯状分枝杆菌:一种不常见的皮肤感染病因。

IF 1.1 Q4 INFECTIOUS DISEASES IDCases Pub Date : 2024-12-15 eCollection Date: 2025-01-01 DOI:10.1016/j.idcr.2024.e02132
Biruk Amare, Andrew Mangano, Moumita Sarker, Sagun Adhikari
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引用次数: 0

摘要

龟分枝杆菌是一种生长迅速的非结核分枝杆菌(NTM),在环境中无处不在,与皮肤和软组织感染有关(1)。由于龟分枝杆菌是一种机会性感染,它可以表现为皮肤脓肿、蜂窝织炎、骨髓炎、肺部感染或弥散性感染,特别是在免疫系统受损或潜在肺部疾病如囊性纤维化或支气管扩张的个体中。龟分枝杆菌是致病性最强的快速生长分枝杆菌之一。诊断RGM并将其与结核分枝杆菌区分开来非常重要,因为这两种微生物的公共卫生跟踪和管理不同。抗生素敏感性测试也可以为RGM的物种鉴定提供有价值的线索,因为每个物种都有特定的体外抗生素敏感性模式(2)。尽管Chelonae的发病率正在增加,但这些感染经常被误诊。本病例报告讨论了临床表现,诊断挑战,早期经验治疗的基本原理,以及对Chelonae感染的治疗选择,强调了免疫功能低下个体及时干预的重要性。
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Disseminated Mycobacterium Chelonae infection in an immunocompromised adult: An uncommon etiology of skin infection.

Mycobacterium Chelonae is a rapidly growing nontuberculous mycobacterium (NTM) that is ubiquitous in the environment and is associated with skin and soft tissue infections (1). Because Mycobacterium Chelonae is an opportunistic infection, it can present as skin abscess, cellulitis, osteomyelitis, pulmonary infection or disseminated infections, particularly in individuals with compromised immune systems or underlying lung conditions such as cystic fibrosis or bronchiectasis. M.Chelonae is one of the most pathogenic rapidly growing mycobacteria (RGM). Diagnosing RGM and distinguishing it from Mycobacterium tuberculosis is important because public health tracking and management is different in these two organisms. Antibiotic susceptibility testing can also provide valuable clues to the species identification of RGM as each species has a specific in vitro antibiotic susceptibility pattern (2). Although incidence of M. Chelonae is increasing, these infections often remain misdiagnosed. This case report discusses the clinical presentation, diagnostic challenges, the rationale for early empiric treatment, and therapeutic options for M. Chelonae infection, emphasizing the importance of timely intervention in immunocompromised individuals.

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来源期刊
IDCases
IDCases INFECTIOUS DISEASES-
CiteScore
2.60
自引率
6.70%
发文量
300
审稿时长
10 weeks
期刊最新文献
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