5-氨基异恶唑在氢化物转移策略下构建氮杂环中的不同应用

IF 4.6 1区 化学 Q1 CHEMISTRY, ORGANIC Organic Chemistry Frontiers Pub Date : 2025-01-17 DOI:10.1039/d4qo02059f
Mengzhe Pan, Feng-Wei Guo, Xinjie Sun, Jie Zhang, Wei Lu, Lubin Xu, Fangzhi Hu, Shuai-Shuai Li
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引用次数: 0

摘要

利用不同的Lewis酸对氨基进行解环/贝克曼重排、脱芳-螺旋环化或N,N ' -二烷基化,从而实现了5-氨基异唑在不同类型四氢喹啉和四氢喹唑类化合物中氢化物转移的分散应用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Divergent application of 5-amino-isoxazoles for the construction of nitrogen heterocycles via the hydride transfer strategy
The hydride transfer-enabled divergent application of 5-amino-isoxazoles for the controllable construction of diverse tetrahydroquinolines and tetrahydroquinazolines was disclosed unprecedentedly by the process of ring-cleavage/Beckmann rearrangement, dearomative-spirocyclization, or N,N′-dialkylation of the amino group with the employment of different Lewis acids.
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来源期刊
Organic Chemistry Frontiers
Organic Chemistry Frontiers CHEMISTRY, ORGANIC-
CiteScore
7.90
自引率
11.10%
发文量
686
审稿时长
1 months
期刊介绍: Organic Chemistry Frontiers is an esteemed journal that publishes high-quality research across the field of organic chemistry. It places a significant emphasis on studies that contribute substantially to the field by introducing new or significantly improved protocols and methodologies. The journal covers a wide array of topics which include, but are not limited to, organic synthesis, the development of synthetic methodologies, catalysis, natural products, functional organic materials, supramolecular and macromolecular chemistry, as well as physical and computational organic chemistry.
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