胆囊癌胆囊切除术后5年诊断为异时性胰胆管畸形的胰腺癌，可随访影像学直到癌症发病：1例报告和文献回顾。

IF 1 4区医学 Q3 MEDICINE, GENERAL & INTERNAL Internal Medicine Pub Date : 2025-01-15 DOI:10.2169/internalmedicine.4581-24

Masaki Miyazawa, Masahiro Yanagi, Tomoyoshi Chiba, Kazuki Nagai, Hidenori Kido, Saiho Sugimoto, Masaki Nishitani, Noriaki Orita, Noboru Takata, Tomoyuki Hayashi, Akihiro Seki, Hidetoshi Nakagawa, Kouki Nio, Takeshi Terashima, Noriho Iida, Shinya Yamada, Hajime Takatori, Tetsuro Shimakami, Eishiro Mizukoshi, Masao Honda, Taro Yamashita

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引用次数: 0

摘要

胰胆管畸形（PBM）是否是胰腺癌（PC）的危险因素尚不清楚。我们报告一例在胆囊癌胆囊切除术后诊断为异时性PC并PBM的病例，其中随访成像直到PC发病。一名63岁的男性，5年前被诊断为胆囊癌并接受了胆囊切除术，后来患上了胰腺炎。胰腺造影显示PBM，胰管刷细胞学显示腺癌。回顾随访图像，发现胆囊切除术前未见的胰腺形态异常逐渐进展，提示胆胰反流导致胰腺癌发生。

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Metachronous Pancreatic Cancer with Pancreaticobiliary Maljunction Diagnosed Five Years after Cholecystectomy for Gallbladder Cancer, in Which Follow-up Imaging was Possible Until the Onset of Cancer: A Case Report and Review of the Literature.

Whether or not pancreaticobiliary maljunction (PBM) is a risk factor for pancreatic cancer (PC) is unclear. We present a case of metachronous PC with PBM diagnosed after cholecystectomy for gallbladder cancer, in which follow-up imaging was possible until PC onset. A 63-year-old man who had been diagnosed with gallbladder cancer and had undergone cholecystectomy 5 years earlier developed pancreatitis. Pancreatography revealed PBM, and pancreatic duct brush cytology revealed adenocarcinoma. On reviewing the follow-up images, pancreatic morphological abnormalities, which had not been observed before cholecystectomy, were found to have gradually progressed, suggesting that biliopancreatic reflux led to pancreatic carcinogenesis.

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来源期刊

Internal Medicine 医学-医学：内科

CiteScore

1.90

自引率

8.30%

发文量

审稿时长

2.2 months

期刊介绍： Internal Medicine is an open-access online only journal published monthly by the Japanese Society of Internal Medicine. Articles must be prepared in accordance with "The Uniform Requirements for Manuscripts Submitted to Biomedical Journals (see Annals of Internal Medicine 108: 258-265, 1988), must be contributed solely to the Internal Medicine, and become the property of the Japanese Society of Internal Medicine. Statements contained therein are the responsibility of the author(s). The Society reserves copyright and renewal on all published material and such material may not be reproduced in any form without the written permission of the Society.