未分化甲状腺癌的孤立性肠转移。一份病例报告和文献综述。

IF 2.5 3区 医学 Q2 GASTROENTEROLOGY & HEPATOLOGY International Journal of Colorectal Disease Pub Date : 2025-01-22 DOI:10.1007/s00384-025-04804-1
Mariacristina Cartillone, Iacopo Sarvà, Chiara Mazzone, Giorgia Litrico, Maria Carolina Picardo, Francesco Saverio Latteri, Gaetano La Greca
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引用次数: 0

摘要

在这篇文章中,我们的目的是证明甲状腺癌可以转移到小肠。本病例报告涉及一名66岁的女性,她于2019年接受了甲状腺全切除术,组织病理学显示为3A未分化甲状腺癌。她有肠梗阻的症状,包括腹痛、恶心和呕吐。甲状腺癌占所有恶性肿瘤的不到4%,是最常见的内分泌恶性肿瘤。主要类型为乳头状癌,通常预后良好。相比之下,低分化甲状腺癌预后较差,术后5年生存率为66%。常见的转移部位包括肺、脑和骨骼,很少发生在肾脏、脾脏、肾上腺和卵巢等器官。肠道转移极为罕见,文献记载的胃肠道转移病例少于15例。本病例强调了甲状腺癌转移到小肠的罕见可能性,强调了临床医生有必要考虑甲状腺癌病史并出现胃肠道症状的患者的转移扩散。
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Isolated metastasis of the bowel from undifferentiated thyroid carcinoma. A case report and a literature review.

In this article, we aim to demonstrate that thyroid carcinoma can metastasize to the small bowel. This case report involves a 66-year-old woman who underwent total thyroidectomy surgery in 2019, with histopathology revealing a 3A undifferentiated thyroid cancer. She presented with symptoms of bowel obstruction, including abdominal pain, nausea, and vomiting. Thyroid carcinoma accounts for less than 4% of all malignant neoplasms, making it the most common endocrine malignancy. The predominant type is papillary carcinoma, which generally has a favorable prognosis. In contrast, poorly differentiated thyroid cancers have a poor prognosis, with a 5-year postoperative survival rate of 66%. Common metastatic sites include the lungs, brain, and bones, with rare occurrences in organs such as the kidneys, spleen, adrenal glands, and ovaries. Intestinal metastases are extremely rare, with fewer than 15 cases of gastrointestinal localization documented in the literature. This case highlights the rare possibility of thyroid carcinoma metastasizing to the small bowel, emphasizing the need for clinicians to consider metastatic spread in patients with a history of thyroid cancer who present with gastrointestinal symptoms.

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来源期刊
CiteScore
4.90
自引率
3.60%
发文量
206
审稿时长
3-8 weeks
期刊介绍: The International Journal of Colorectal Disease, Clinical and Molecular Gastroenterology and Surgery aims to publish novel and state-of-the-art papers which deal with the physiology and pathophysiology of diseases involving the entire gastrointestinal tract. In addition to original research articles, the following categories will be included: reviews (usually commissioned but may also be submitted), case reports, letters to the editor, and protocols on clinical studies. The journal offers its readers an interdisciplinary forum for clinical science and molecular research related to gastrointestinal disease.
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